The University of Tennessee Graduate School of Medicine, Knoxville



The Department of Surgery

Deidra J. Mountain, PhD

Associate Professor
Division of Vascular & Endovascular Surgery
Vascular Research Laboratory

Research Focus

Vascular Biology; Cellular and Molecular Vaculopathy; Intimal Hyperplasia, Restenosis, Graft Failure; Research Education

Education

Postgradaute School
James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN

Post-Doctoral Fellowship
Vascular Biology, University of Tennessee Graduate School of Medicine

Current Publications

Freeman BM, Univers J, Fisher RK, Kirkpatrick SS, Klein FA, Freeman MB, Mountain DJH, Grandas OH.
Testosterone replacement attenuates intimal hyperplasia development in an androgen deficient model of vascular injury. Journal of Surgical Research. 2016 Aug 10. [Epub ahead of print]

Bools LM, Fisher RK, Grandas OH, Kirkpatrick SS, Arnold JD, Goldman MH, Freeman MB, Mountain DJH.
Comparative analysis of polymers for short interfering RNA delivery in vascular smooth muscle cells. The Journal of Surgical Research. 2015 Nov;199(1):266-73. Epub 2015 Jul 17.

Huang L, Pu C, Fisher RK, Mountain DJ, Gao Y, Liaw PK, Zhang W, He W.
A Zr-based bulk metallic glass for future stent applications: Materials properties, finite element modeling, and in vitro human vascular cell response. Acta Biomaterialia. 2015 Oct;25:356-68. Epub 2015 Jul 7.

Freeman BM, Mountain DJH, Brock TC, Chapman JR, Kirkpatrick SS, Freeman MB, Klein FA, Grandas OH.
Low testosterone elevates interleukin family cytokines in a rodent model: a possible mechanism for the potentiation of vascular disease in androgen-deficient males. Journal of Surgical Research. 2014 Jul;190(1):319-27.

Current Presentations

Univers J, Mountain D, Freeman B, Fisher R, Kirkpatrick S, Klein F, Freeman M, Grandas O. Urotensin's mechanistic role for development of intimal hyperplasia in androgen deficient males. Presented at Academic Surgical Congress; 2016 Feb 2-4; Jacksonville, FL.

Buckley MR, Mountain DJ, Bools LM, Kirkpatrick SS, Whelan J, Terry P, Freeman MB, Grandas OH. Dietary Zyflamend inhibits intimal hyperplasia development via the attenuation of macrophage infiltration in a rodent model of vascular injury. Presented at Southern Association for Vascular Surgery; 2016 Jan 20-23; Cancun, Mexico.

Bools L, Buckley R, Mountain DJH, Kirkpatrick S, Whelan J, Terry P, Freeman MB, Grandas O. A poly-herbal dietary supplement, Zyflamend, inhibits matrix metalloproteinase expression and attenuates intimal hyperplasia in a rodent model of vascular disease. Presented at Society for Vascular Surgery; 2015 Jun 17-20; Chicago, IL.

Freeman BM, Mountain DJH, Brock TC, Chapman J, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Freeman MB, Klein FA, Grandas OH. Testosterone replacement attenuates hyperplasia development in an androgen deficient model of vascular injury independent of MMP regulation. Presented at Vascular Research Initiatives Conference and Arteriosclerosis, Thrombosis and Vascular Biology Peripheral Vascular Disease Scientific Sessions; 2015 May 6-9; San Francisco, CA.

Bools LM, Mountain DJ, Fisher RK, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Freeman MB, Grandas OH. Comparative analysis of polymers for siRNA delivery in vascular smooth muscle cells. Presented at 10th Annual Academic Surgical Congress; 2015 Feb 3-5; Las Vegas, NV.

Bools L, Buckley R, Mountain D, Kirkpatrick S, Whelan J, Terry P, Freeman M, Grandas O. Zyflamend: A poly-herbal extract, inhibits matrix metalloproteinases expression and attenuates intimal hyperplasia in a rodent model of vascular disease. Presented at Southern Association for Vascular Surgery; 2015 Jan 14-17; Scottsdale, AZ.

Bools LM, Mountain DJH, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Freeman MB, Grandas OH. Comparative analysis of polymers for siRNA delivery in vascular smooth muscle cells. Presented at Tennessee Chapter of American College of Surgeons; 2014 Aug 8-10; Buchanan, TN.

Freeman BM, Mountain DJH, Brock TC, Chapman JR, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Klein FA, Freeman MB, Grandas OH. Low testosterone elevates pro-inflammatory interleukin family cytokines: A possible mechanism for the potentiation of vascular disease in androgen deficient males. Presented at American Urological Assocation; 2014 May 16-21; Hollywood, FL.

Freeman BM, Mountain DJ, Brock TC, Chapman JR, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Freeman MB, Klein FA, Grandas OH. Low testosterone elevates pro-inflammatory interleukin family cytokines: A possible mechanism for the potentiation of vascular disease in androgen deficient males. Presented at Academic Surgical Congress; 2014 Feb 4-6; San Diego, CA.

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