The Department of Surgery

Deidra J. Mountain, PhD

Professor
Division of Vascular & Endovascular Surgery
Vascular Research Laboratory

https://orcid.org/0000-0002-0217-7462

Research Focus

The Vascular Research Laboratory performs research investigating the development of intimal hyperplasia and restenosis, the most common chronic complications following balloon angioplasty, vascular stenting, and vascular bypass graft surgery. Significant efforts are focused on designing nanoparticles for targeted vascular drug delivery aimed at hyperplasia prevention. The lab's primary objective is the development of therapeutic interventions to increase the success of endovascular procedures and improve long-term vascular surgical outcomes.

Education

Gradaute School
Biomedical Sciences, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN

Post-Doctoral Fellowship
Vascular Biology, University of Tennessee Graduate School of Medicine

Professional Affiliations

American Heart Association
Association for Academic Surgery
Society of Vascular Surgery
Controlled Release Society

Current Publications

Qualls ML, Hagewood H, Lou J, Mattern-Schain SI, Zhang X, Mountain DJ, Best MD.
Bis-boronic acid liposomes for carbohydrate recognition and cellular delivery. Chembiochem. 2022 Aug 31:e202200402. doi: 10.1002/cbic.202200402. Online ahead of print.

Sojka PA, Smith SM, Greenacre CB, Newkirk K, Mountain DJH.
Qualitative investigation of µ- and κ-opioid receptor distribution in the brains of budgerigars (Melopsittacus undulatus). Am J Vet Res. 2022 May 21;83(7):ajvr.21.04.0052. doi: 10.2460/ajvr.21.04.0052.

Current Presentations

West PC, Kinnear TW, Mattern-Schain SI, Kirkpatrick SS, Arnold JD, Buckley MR, Freeman MB, Grandas OH, McNally MM, Mountain DJH. Assembly of Non-Cationic Lipid Nanoparticles for Optimized RNA Drug Payload and Efficacy. Presented at Controlled Release Society 2022 Annual Meeting; 2022 July-11; Montreal, Canada.

McAdams CD, Grimsley LB, West PC, Arnold JD, Buckley RM, Dieter RA, Freeman MB, Grandas OH, McNally MM, Stevens SL. Lipid Nanoparticles Functionalized for Sub-Endothelial Matrix Targeting in Lower Extremity Vessels. Presented at Academic Surgical Congress 2022; 2022 February-1; Orlando, Florida.

Grimsely L, West P, Arnold J, Buckley R, Dieter R, Freeman M, Grandas O, McNally M, Stevens S, Mountain D. Lipid Nanoparticles Functionlized for Sub-Endothelial Matrix Targeting in Lower Extremity Vessels. Presented at Academic Surgical Congress ; 2022 February-1; Orlando, Florida.