The Department of Surgery

Michael B. Freeman, MD, FACS

Professor
Interim Chairman
Chief, Division of Vascular and Endovascular Surgery, Program Director, Vascular Surgery Fellowship
Division of Vascular & Endovascular Surgery

Clinical Focus

Aneurysms, Carotid Disease, Peripheral Arterial Disease, Endovascular Treatment of Vascular Disease

Research Focus

Vascular Wall Biology

Education

Medical School
Medical College of Georgia, Augusta, GA

Internship
General Surgery, Barnes Hospital, Washington University School of Medicine, St. Louis, MO

Residency
General Surgery, Barnes Hospital, Washington University School of Medicine, St. Louis, MO

Fellowship
Vascular Surgery, Barnes Hospital, Washington University School of Medicine, St. Louis, MO

Certifications

American Board of Surgery
Added Qualifications in Vascular Surgery

Professional Affiliations

American College of Surgeons
Association of Academic Surgeons
Southern Association for Vascular Surgery
Southeastern Surgical Congress
Association of Program Directors in Vascular Surgery
Society of Vascular Surgeons
American Vascular Research Organization

Current Publications

Buckley MR, Terry PD, Kirkpatrick SS, Arnold JD, McNally MM, Grandas OH, Freeman MB, Goldman MH, Whelan J, Mountain DJ.
Dietary supplementation with Zyflamend poly-herbal extracts and fish oil inhibits intimal hyperplasia development following vascular intervention. Nutrition Research (New York, N.Y.). 2019 Jun 8;68:34-44.

Mountain DJH, Kirkpatrick SS, Arnold JD, Buckley MR, McNally MM, Stevens SL, Freeman MB, Grandas OH.
The efficacy of systemic doxycycline adminstration as an inhibitor of intimal hyperplasia after balloon angioplasty arterial injury. Annals of Vascular Surgery. 2019 May;57:201-209. Epub 2019 Jan 24.

Univers J, Long C, Tonks SA, Freeman MB.
Systemic hypersensitivity reaction to endovascular stainless steel stent. Journal of Vascular Surgery. 2018 Feb;67(2):615-617. Epub 2017 Dec 13.

Fisher RK, Mattern-Schain SI, Best MD, Kirkpatrick SS, Freeman MB, Grandas OH, Mountain DJH.
Improving the efficacy of liposome-mediated vascular gene therapy via lipid surface modifications Journal of Surgical Research. 2017 Nov;219:136-144. Epub 2017 Jun 27.

Schlieve T, Carlson ER, Freeman M, Buckley R, Arnold J.
The double mandibular osteotomy for vascular and tumor surgery of the parapharyngeal space. Journal of Oral and Maxillofacial Surgery. 2017 May;75(5):1046-1061. Epub 2016 Nov 15.

Freeman BM, Univers J, Fisher RK, Kirkpatrick SS, Klein FA, Freeman MB, Mountain DJH, Grandas OH.
Testosterone replacement attenuates intimal hyperplasia development in an androgen deficient model of vascular injury. Journal of Surgical Research. 2017 Jan;207:53-62. Epub 2016 Aug 10.

Jagadish M, McNally MM, Heidel RE, Teffeteller S, Arnold JD, Freeman M, Stevens SL, Grandas OH, Goldman MH.
Diabetic foot ulcers: The importance of patient comorbidity recognition and total contact casting in successful wound care. The American Surgeon. 2016 Aug;82(8):733-736.

Current Presentations

Grimsley L, Fisher R, Dieter R, Arnold J, Buckley R, McNally M, Freeman M, Mountain D, Grandas O. Liposomal nanocarriers designed for sub-endothelial matrix targeting under vascular sheer stress. Presented at Tennessee American College of Surgeons Annual Meeting; 2019 Aug 8-11; Chattanooga, TN.

Grimsley LB, Dieter RA, Arnold JD, Buckley MR, McNally MM, Freeman MB, Grandas OH, Mountain DJH. Dual-ligand modified liposomal nanoparticles multifunctionalized for spatially controlled delivery of gene therapeutics. Presented at Society of Vascular Surgery Vascular Research Initiatives Conference; 2019 May 13; Boston, MA.

Grimsley LB, Fisher RK, Mattern-Schain SI, Dieter RA, Arnold JD, Buckley MR, McNally MM, Freeman MB, Grandas OH, Best MD, Mountain DJ. Cell mimetic liposomal nanocarriers tailored for cell-type specific delivery of vascular molecular therapeutics. Presented at Academic Surgical Congress; 2019 Feb 5-7; Houston, TX.

Grimsley L, Fisher R, Dieter R, Arnold J, Buckley R, McNally M, Freeman M, Mountain D, Grandas O. Liposomal nanocarriers designed for sub-endotheial matrix targeting under vascular sheer stress. Presented at Southern Association of Vascular Surgery; 2019 Jan 23-26; Boca Raton, FL.

Fisher RK, Mattern-Schain SI, Kirkpatrick SS, Best MD, Dieter RA, Arnold JD, Buckley MR, McNally MM, Freeman MB, Grandas OH, Mountain DJH.. A simple and efficient method for the assembly siRNA-loaded neutral stealth liposomes. Presented at 16th Annual International Nanomedicine & Drug Delivery Symposium; 2018 Sep 21-23; Portland, OR.

Grimsley LB, Fisher RK, Mattern-Schain SI, Dieter RA, Arnold JD, Buckley MR, McNally MM, Freeman MB, Grandas OH, Best MD, Mountain DJ. Cell mimetic liposomal nanocarriers tailored for vascular smooth muscle cell molecular therapeutics. Presented at Tennessee American College of Surgeons Annual Meeting; 2018 Aug 10-12; Nashville, TN.

Fisher RK, Mattern-Schain SI, Kirkpatrick SS, Best MD, Arnold JD, Buckley MR, McNally MM, Freeman MB, Grandas OH, Mountain DJ. A one-step scalable assembly method for PEGylated liposomes with efficient siRNA-loading and enhanced cellular association. Presented at Controlled Release Society Annual Meeting & Exposition; 2018 Jul 22-25; New York, NY.

Gregory LB, Grandas OH, Tayidi IT, Buckley MR, Arnold JA, Cantafio AW, Stevens SL, Freeman MB, Goldman MH, McNally MM. Contemporary clinical and financial analysis of open versus percutaneous mechanical thrombectomy for occluded hemodialysis access Presented at Southern Association of Vascular Surgery; 2018 Jan 16-20; Scottsdale, AZ.

Cudnik J, Grimsley L, Fisher R, Kirkpatrick S, Dieter R, Freeman M, Mountain D, Grandas O. Liposomal nanocarriers designed for spatially-controlled targeting under vascular sheer stress. Presented at Southern Association of Vascular Surgery; 2018 Jan 16-20; Scottsdale, AZ.

Cudnik J, West P, Fisher R, Mattern-Schain S, Best M, Kirkpatrick S, Freeman M, Grandas O, Mountain D. Sub-endothelial matrix targeted liposomal nanoparticles for vascular terapeutics. Presented at Society for Vascular Surgery Annual Meeting; 2017 May 31 - Jun 3; San Diego, CA.

Cudnik J, West P, Fisher R, Mattern-Schain S, Best M, Kirkpatrick S, Freeman M, Grandas O, Mountain D. Sub-Endothelial matrix targeted liposomal nanoparticles for vascular therapeutics. Presented at Arteriosclerosis, Thrombosis, and Vascular Biology/Peripheral Vascular Disease; 2017 May 4-6; Minneapolis, MN.

Tonks S, Lee S, Freeman MB, Grandas OH, Stevens SL, Goldman MH, McNally MM, Arnold JD. Threatened AV access with central venous obstruction: Thoracic outlet decompression versus hero graft. Presented at Southeastern Surgical Congress; 2017 Feb 25-28; Nashville, TN.

Fisher RK, Mattern-Schain SI, Best MD, Kirkpatrick SS, Freeman MB, Grandas OH, Mountain DJ. Improving the efficacy of liposomal-mediated vascular gene therapy via lipid surface modifications. Presented at 12th Annual Academic Surgical Congress; 2017 Feb 7-9; Las Vegas, NV.

Warner K, Buckley R, Mountain D, Kirkpatrick S, Whelan J, Terry P, Goldman M, Freeman M, Grandas O. Zyfamend+Wholemega fatty acid combinatorial therapy inhibits intimal hyperplasia via the attenuation of M2 macrophage differentiation in a rodent model of vascular injury. Presented at Southern Association for Vascular Surgery; 2017 Jan 18-21; Naples, FL.

Univers J, Long C, Tonks SA, Freeman MB. Systemic hyper-sensitivity reaction to endovascular stainless steel stent. Presented at Southern Association for Vascular Surgery; 2017 Jan 18-21; Naples, FL.