The University of Tennessee Graduate School of Medicine, Knoxville



The Department of Medicine

Jonathan S. Wall, PhD

Professor
Amyloidosis and Cancer Theranostics Program
Preclinical and Diagnostic Molecular Imaging Laboratory

Research Focus

Preclinical diagnostic imaging of amyloid diseases

Education

Postdoctoral
University of Tennessee Medical Center
Human Immunology & Cancer Program
Knoxville, TN (January 1995- April 1997)

Graduate University of Essex
Department of Chemistry & Biological Chemistry, Colchester, UK (October 1991- December 1994).
Ph.D conferred July 1995

Undergraduate
University of Essex
Department of Biology
Colchester, UK (October 1987-June 1991).
BSc. (Hons.) Biological Sciences, July 1991

Faculty Appointments

Professor, University of Tennessee Graduate School of Medicine, Knoxville, TN (June 2009 - present)
Associate Professor, University of Tennessee Graduate School of Medicine, Knoxville, TN (June 2003 - June 2009)
Assistant Professor, University of Tennessee Graduate School of Medicine, Knoxville, TN (April 1997 - June 2003)
Adjunct Associate Professor, Department of Small Animal Clinical Sciences, University of Tennessee, College of Veterinary Medicine, Knoxville, TN (July 2007 - present)
Director, Preclinical and Diagnostic Molecular Imaging Laboratory, University of Tennessee Graduate School of Medicine, Knoxville, TN (11/2005 - present)

Awards and Honors

2011 World Molecular Imaging Congress
San Diego, California
Inveon Image of the Year Award 2011
Translational Image of the Year Award 2011

GSM Faculty Award 2011
GSM Spirit Award
University of Tennessee Graduate School of Medicine, June 2011

Visiting Professor
Amyloid, melanoma and the missing molecular link
University of Uppsala,
Uppsala, Sweden, April 7th 2011

Visiting Professor
Animal imaging in basic, clinical, and translational research
Biochemistry and Molecular Biology Seminar Series,
The Mayo Clinic,
Rochester, MN. March 1st 2011

2010 World Molecular Imaging Congress
Kyoto, Japan
Inveon Image of the Year 2010
Best Presented Image of the Year 2010

Memberships

Member of the American Association of Immunologists (2001-present)
Society of Nuclear Medicine (May 2007-present)
American Association for Laboratory Animal Science (Gold Membership; 2007- present)
International Society of Amyloidosis (Jan 2008- present)
Honorary member Phi Zeta – the Honor Society of Veterinary Medicine (April 2008-present)

Current Publications

Kennel SJ, Macy S, Wooliver C, Huang Y, Richey T, Heidel E, Wall JS.
Phagocyte depletion inhibits AA amyloid accumulation in AEF-induced huIL-6 transgenic mice. Amyloid. 2014 Mar;21(1):45-53.

McLaughlin MF, Robertson D, Mirzadeh S, Pevsner PH, Wall JS, Kennel SJ.
LnPO4 nanoparticles doped with Ac-225 and sequestered daughters for targeted alpha therapy. Cancer Biotherapy and Radiopharmaceuticals. 2014 Feb;29(1):34-41.

del Pozo-Yauner L, Gonzalez Andrade M, Perez Carreon JI, Wall JS, Sanchez-Lopez R, Rodriguez-Ambriz SL, Fernandez-Velasco DA, Ochoa-Leyva A.
The N-terminal strand modulates immunoglobulin light chain fibrillogenesis. Biochemical and Biophysical Research Communications. 2014 Jan 10;443(2):495-9.

Stout D, Berr SS, LeBlanc A, Kalen JD, Osborne D, Price J, Schiffer W, Kuntner C, Wall J.
Guidance for methods descriptions used in preclinical imaging papers. Molecular Imaging. 2013;12(0):1-15.

Hamill JJ, Sunderland JJ, Leblanc AK, Kojima CJ, Wall J, Martin EB.
Evaluation of CT-based lean-body SUV. Medical Physics. 2013 Sep;40(9):092504.

Wall JS, Williams A, Richey T, Stuckey A, Huang Y, Wooliver C, Macy S, Heidel E, Gupta N, Lee A, Rader B, Martin EB, Kennel SJ.
A Binding-Site Barrier Affects Imaging Efficiency of High Affinity Amyloid-Reactive Peptide Radiotracers In Vivo. PLoS ONE. 2013 Jun 4;8(6):e66181.

Martin EB, Williams A, Heidel E, Macy S, Kennel SJ, Wall JS.
Peptide p5 binds both heparinase-sensitive glycosaminoglycans and fibrils in patient-derived AL amyloid extracts. Biochemical and Biophysical Research Communications. 2013 Jun 21;436(1):85-9

Rowe JA, Morandi F, Wall JS, Akula M, Kennel SJ, Osborne D, Martin EB, Galyon GD, Long MJ, Stuckey AC, Leblanc AK .
Whole-body biodistribution of 3'-deoxy-3'-[18f]fluorothymidine (18flt) in healthy adult cats. Veterinary Radiology and Ultrasound. 2013 May-Jun;54(3):299-306.

Wall JS, Richey T, Macy S, Heidel E, Wooliver C, Kennel SJ.
A novel method for quantifying peripheral tissue amyloid load by using the radiolabeled amyloidophilic peptide, p5. Amyloid. 2013 Mar;20(1):21-6.

Jones MP, Morandi F, Wall JS, Long MJ, Stuckey AC, LeBlanc AK .
Distribution of 2-deoxy-2-fluoro-d-glucose in the coelom of healthy bald eagles (Haliaeetus leucocephalus). American Journal of Veterinary Research. 2013 Mar;74(3):426-32.

McLaughlin MF, Woodward J, Boll RA, Wall JS, Rondinone AJ, Kennel SJ, Mirzadeh S, Robertson JD.
Gold Coated Lanthanide Phosphate Nanoparticles for Targeted Alpha Generator Radiotherapy. PLoS ONE. 2013;8(1):e54531.

Wall JS, Kennel SJ, Williams A, Richey T, Stuckey A, Huang Y, Macy S, Donnell R, Barbour R, Seubert P, Schenk D .
AL Amyloid Imaging and Therapy with a Monoclonal Antibody to a Cryptic Epitope on Amyloid Fibrils. PLoS ONE. 2012;7(12):e52686.

Osborne DR, Yan S, Stuckey A, Pryer L, Richey T, Wall JS.
Characterization of X-ray Dose in Murine Animals Using microCT, a New Low-Dose Detector and nanoDot Dosimeters. PLoS ONE. 2012;7(11):e49936.

Bruckbauer A, Zemel MB, Thorpe T, Akula MR, Stuckey AC, Osborne D, Martin EB, Kennel S, Wall JS.
Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutrition and Metabolism. 2012 Aug 22;9(1):77.

Wall JS, Richey T, Williams A, Stuckey A, Osborne D, Martin E, Kennel SJ.
Comparative analysis of peptide p5 and serum amyloid P component for imaging AA amyloid in mice using dual-isotope SPECT. Molecular Imaging and Biology. 2012 Aug;14(4):402-7.

Leblanc AK, Miller AN, Galyon GD, Moyers TD, Long MJ, Stuckey AC, Wall JS, Morandi F.
Preliminary evaluation of serial 18fdg-pet/ct to assess response to toceranib phosphate therapy in canine cancer. Veterinary Radiology and Ultrasound. 2012 May-Jun;53(3):348-57.

Gotoh M, Fujiwara Y, Yue J, Liu J, Lee S, Fells J, Uchiyama A, Murakami-Murofushi K, Kennel S, Wall J, Patil R, Gupte R, Balazs L, Miller DD, Tigyi GJ.
Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis. Biochemical Society Transactions. 2012 Feb;40(1):31-6.

Wall JS, Richey T, Stuckey A, Donnell R, Oosterhof A, van Kuppevelt TH, Smits NC, Kennel SJ.
SPECT imaging of peripheral amyloid in mice by targeting hyper-sulfated heparan sulfate proteoglycans with specific scFv antibodies. Nuclear Medicine and Biology. 2012 Jan;39(1):65-75.

Souza MJ, Wall JS, Stuckey A, Daniel GB.
Static and dynamic 18fdg-pet in normal hispaniolan amazon parrots (amazona ventralis). Veterinary Radiology and Ultrasound. 2011 May-Jun;52(3):340-4.

Lyons JA, Dickson PI, Wall JS, Passage MB, Ellinwood NM, Kakkis ED, McEntee MF.
Arterial pathology in canine mucopolysaccharidosis-I and response to therapy. Laboratory Investigation. 2011 May;91(5):665-74.

Kestler DP, Foster JS, Bruker CT, Prenshaw JW, Kennel SJ, Wall JS, Weiss DT, Solomon A.
ODAM expression inhibits human breast cancer tumorigenesis. Breast Cancer: Basic and Clinical Research. 2011;5:73-85.

Woodward J, Kennel SJ, Stuckey A, Osborne D, Wall J, Rondinone AJ, Standaert RF, Mirzadeh S, Standaert RF.
LaPO4 nanoparticles doped with actinium-225 that partially sequester daughter radionuclides. Bioconjugate Chemistry. 2011 Apr 20;22(4):766-76.

Stuart CA, Ross IR, Howell MEA, McCurry MP, Wood TG, Ceci JD, Kennel SJ, Wall J, Wood TG.
Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake. Brain Research. 2011 Apr 12;1384:15-22.

Davern S, Murphy CL, O'Neill H, Wall JS, Weiss DT, Solomon A.
Effect of lysine modification on the stability and cellular binding of human amyloidogenic light chains. Biochimica et Biophysica Acta - Molecular Basis of Disease. 2011 Jan;1812(1):32-40.

Smits NC, Kurup S, Rops AL, Ten Dam GB, Massuger LF, Hafmans T, Turnbull JE, Spillmann D, Li J-P, Kennel SJ, Wall JS, Shworak NW, Dekhuijzen PNR, Van Der Vlag J, Van Kuppevelt TH.
The heparan sulfate motif (GlcNS6S-IdoA2S)3, common in heparin, has a strict topography and is involved in cell behavior and disease. Journal of Biological Chemistry. 2010 Dec 24;285(52):41143-51.

Kennel SJ, Huang Y, Zeng WB, Stuckey A, Wall J.
Kinetics of vascular targeted monoclonal antibody. Current Drug Delivery. 2010 Dec;7(5):428-35.

Phipps JE, Kestler DP, Foster JS, Kennel SJ, Donnell R, Weiss DT, Solomon A, Wall JS .
Inhibition of pathologic immunoglobulin-free light chain production by small interfering RNA molecules. Experimental Hematology. 2010 Nov;38(11):1006-13.

Wall JS, Kennel SJ, Stuckey AC, Long MJ, Townsend DW, Smith GT, Wells KJ, Fu Y, Stabin MG, Weiss DT, Solomon A.
Radioimmunodetection of amyloid deposits in patients with AL amyloidosis. Blood. 2010 Sep 30;116(13):2241-4.

Samaan G, Yugo D, Rajagopalan S, Wall J, Donnell R, Goldowitz D, Gopalakrishnan R, Venkatachalam S.
Foxn3 is essential for craniofacial development in mice and a putative candidate involved in human congenital craniofacial defects. Biochemical and Biophysical Research Communications. 2010 Sep 10;400(1):60-5.

Current Presentations

Kennel SJ, Macy S, Wooliver C, Huang Y, Richey T, Heidel RE, Wall JS. Phagocyte depletion inhibits reactive (AA) amyloid accumulation in amyloid enhancing factor-induced human IL-6 transgenic mice Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

Martin EB, Richey T, Stuckey A, Wooliver C, Macy S, Osborne D, Kennel SJ, Wall JS. Detection of cardiac amyloidosis by SPECT/CT imaging using both 125I-serum amyloid P-component and the novel 125I- p5R+14 peptide Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

Wall JS, Williams A, Richey T, Stuckey A, Wooliver C, Macy S, Martin EB, Kennel SJ. Specific accumulation of radiolabeled peptide p5 in cerebral vascular and parenchymal Aß amyloid in mice Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

Martin EB, Kennel SJ, Williams A, Richey T, Stuckey A, Wooliver C, Macy S, Wall JS. Characterization of a novel peptide, p43 optimized for renal and pancreatic amyloid detection Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

Wall JS, Williams A, Richey T, Stuckey A, Huang Y, Wooliver C, Macy S, Heidel RE, Martin EB, Kennel SJ. High affinity amyloid-reactive peptide, p5R, binds non-uniformly to large amyloid deposits due to a binding site barrier effect Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

Wall JS, Donnell R, Richey T, Stuckey A, Martin EB, Kennel SJ. Heparin-binding peptides, basic fibroblast growth factor and p5R bind to different targets in amyloid-laden mice and controls Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

Martin EB, Richey T, Stuckey A, Heidel RE, Lee A, Rader B, Osborne D, Kennel SJ, Wall JS. Characterization of peptide 125I-p5R+14 as an optimized radiotracer for the in vivo detection of ApoA2c amyloidosis. Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

Wall JS, Williams A, Richey T, Stuckey A, Huang Y, Wooliver C, Macy S, Martin EB, Kennel SJ. Soluble, recombinant, receptor for advanced glycation end-products (RAGE) binds AA amyloid in vivo Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

Wall JS, Williams A, Richey T, Stuckey A, Huang Y, Wooliver C, Macy S, Heidel RE, Gupta N, Lee A, Rader B, Martin EB, Kennel SJ. A binding-site barrier affects quantitative imaging capabilities of high-affinity amyloid reactive peptide radiotracer p5R Presented at The Sixth Annual World Molecular Imaging Congress; 2013 Sep 18-21; Savannah, GA.

Wall JS, Richey T, Stuckey A, Wooliver C, Macy S, Osborne D, Martin EB, Kennel SJ. Evaluation of SPECT detection of cardiac amyloidosis in mice by using 125I-p5R+14 peptide or 125I-SAP Presented at The Sixth Annual World Molecular Imaging Congress; 2013 Sep 18-21; Savannah, GA.

Martin EB, Richey T, Stuckey A, Heidel RE, Lee A, Rader B, Osborne D, Kennel SJ, Wall JS. Characterization of peptide 125I-p5R+14 as an optimized radiotracer for the in vivo detection of ApoA2c amyloidosis Presented at The Sixth Annual World Molecular Imaging Congress; 2013 Sep 18-21; Savannah, GA.

Martin EB, Richey T, Stuckey A, Heidel RE, Lee A, Rader B, Osborne D, Kennel SJ, Wall JS. Characterization of peptide 125I-p5R+14 as an optimized radiotracer for the in vivo detection of ApoA2c amyloidosis Presented at The Sixth Annual World Molecular Imaging Congress; 2013 Sep 18-21; Savannah, GA.

Wall JS, Richey T, Stuckey A, Akula M, Kabalka G, Macy S, Martin EB, Kennel SJ. Preliminary evaluation of [18F]SFB- and [18F]FBAM-labeled amyloidophilic peptides in mice with visceral amyloidosis Presented at The Sixth Annual World Molecular Imaging Congress; 2013 Sep 18-21; Savannah, GA.

Wall JS. The Role of Molecular Imaging and Correlative Studies in the Development of Biologicals for the Treatment and Diagnosis of Amyloidosis Presented at The Sixth Annual World Molecular Imaging Congress, Siemens Industrial Workshop; 2013 Sep 18-21; Savannah, GA.

Martin EB, Richey T, Stuckey A, Heidel RE, Lee A, Rader B, Osborne D, Kennel SJ, Wall JS. Characterization of peptide 125I-p5R+14 as an optimized radiotracer for the in vivo detection of ApoA2c amyloidosis. Presented at The Sixth Annual World Molecular Imaging Congress; 2013 Sep 18-21; Savannah, GA.

Martin EB, Richey T, Stuckey A, Heidel RE, Lee A, Rader B, Osborne D, Kennel SJ, Wall JS. Characterization of peptide 125I-p5R+14 as an optimized radiotracer for the in vivo detection of ApoA2c amyloidosis. Presented at The Sixth Annual World Molecular Imaging Congress; 2013 Sep 18-21; Savannah, GA.

Osborne D, Wells K, Stuckey A, Wilson S, Wall J, Solomon A. Determination of Cadiac Amyloid Involvement Using 18F-Florbetapir and Dynamic PET Presented at Society of Nuclear Medicine and Molecular Imaging Annual Meeting; 2013 Jul 26-28; Vancouver, Canada.

Akula M, Collier L, LeBlanc A, Stuckey A, Kennel S, Wall J ,Kabalka G. Automated Synthesis of [18F]FTHA and Its Use in PET/CT Imaging Studies in Domestic Cats Presented at 20th International Symposium on Radiopharmaceutical Sciences; 2013 May 12-17; Jeju, Korea.

Wall J. Things to Consider in Preclinical Studies Leading to an eIND Presented at 4th Annual Nuclear Medicine Technologists Meeting; 2013 May 3-5; Gatlinburg, TN.

Wall J, Martin E, Stuckey A, Williams A,  Macy S, Richey T, Kennel SJ. Synthetic Polybasic Peptides for the Detection and Prevention of Amyloidosis Presented at Imaging Pancreatic Beta Cell 5th Workshop; 2013 Apr 15-16; Bethesda, MD.

Wall J. Molecular Imaging and Correlative Studies in Small Animal Cancer Models Presented at American Association for Cancer Research Annual Meeting; 2013 Apr 6-10; Washington DC.

Richey T, Wall J, LeBlanc A, Stuckey A, Martin E, Macy S, Donnell R, Nodit L, Kennel S. Heparin-reactive peptide p5R preferentially binds a subset of MelA+ melanocytes and extracellular melanin - a novel biomarker in metastatic melanoma tumors Presented at World Molecular Imaging Conference; 2012 Sep 5-8; Dublin, Ireland.

Wall J, Donnell R, Richey T, Stuckey A, Higuchi K, Martin E, Kennel S. Heparin-Binding Peptides bFGF and p5R Bind to Different Targets in Amyloid-Laden Mice and Controls Presented at World Molecular Imaging Conference; 2012 Sep 5-8; Dublin, Ireland.

Wall J, LeBlanc A, Richey T, Stuckey A, Martin E, Macy S, Donnell R, Nodit L, Kennel S. Heparin-Reactive Peptide p5R Preferentially Binds a Subset of MelA+ Melanocytes and Extracellular Melanin A Novel Biomarker in Metastatic Melanoma Tumors Presented at World Molecular Imaging Conference; 2012 Sep 5-8; Dublin, Ireland.

Wall J, Richey T, Stuckey A, Williams A, Huang Y, Martin E, Osborne D,  Macy S, Kennel S. Arginine-Rich Peptide p5R Provides Enhanced Binding to Visceral Amyloid Deposits in vitro and in vivo Presented at World Molecular Imaging Conference; 2012 Sep 5-8; Dublin, Ireland.

Martin E, Kennel S, Richey T, Stuckey A, Williams A, Osborne D, Higuchi K, Wall J. Ex vivo Identification and in vivo Validation of a Novel Visceral Amyloid Imaging Peptide Presented at World Molecular Imaging Conference; 2012 Sep 5-8; Dublin, Ireland.

Osborne D, Stuckey A, Kennel S, Richey T, Austin D, Feng B, Wall J. I-131 Rodent Imaging on the Inveon SPECT Platform Using a Novel Blended Collimator Acquisition Method Presented at World Molecular Imaging Conference; 2012 Sep 5-8; Dublin, Ireland.

Osborne D, Aykac D, Gleason S, Kerekes D, Wall J, Gregor J, Paquit V. Whole Body Murine Organ Segmentation Using microCT and Advanced 3D Level Set Algorithms Presented at World Molecular Imaging Conference; 2012 Sep 5-8; Dublin, Ireland.

Wall J, Wells K, Kennel S, Martin E, Osborne D, Solomon A. Radioimmunoimaging of Amyloid Deposits in AL Amyloidosis Presented at Society of Nuclear Medicine Education Webinar Series; 2012 Aug 2; .

Osborne D, Stuckey A, Richey T, Pryer L, Yan S, Wall J. Dose Reduction in Small Animal Imaging Using a Modified Phosphor Screen Presented at Society of Nuclear Medicine Education Webinar Series; 2012 Aug 2; .

Wall J, LeBlanc A, Richey T, Stuckey A, Martin E, Macy S, Kennel S. Specific Binding of Heparin-Reactive Peptides with Melanoma in vitro and in vivo Presented at Society of Nuclear Medicine Annual Meeting; 2012 Jun 9-13; Miami Beach, FL.

Wall J, Richey T, Stuckey A, Williams A, Huang Y, Martin E, Macy S, Kennel S. The Novel Amyloidophilic Peptide p5R Can Be Used to Effectively Identify Murine and Human Amyloid Deposits in vitro and in vivo Presented at Society of Nuclear Medicine Annual Meeting; 2012 Jun 9-13; Miami Beach, FL.

Wall J. What to Consider in Preclinical Studies for an eIND and IND Presented at Society of Nuclear Medicine  Annual Meeting; 2012 Jun 9-13; Miami Beach, FL.

Wall J. Small Animal SPECT Imaging and Correlative Studies Presented at Society of Nuclear Medicine  Annual Meeting; 2012 Jun 9-13; Miami Beach, FL.

Wells K, Wall J, Kennel S, Martin E, Osborne D, Solomon A. Radioimmunoimaging of Patients with AL Amyloidosis Presented at Society of Nuclear Medicine Annual Meeting; 2012 Jun 9-13; Miami Beach, FL.

Martin E, Kennel S, Richey T, Stuckey A, Osborne D, Wall J. The Peptide p5 Binds Rapidly to Visceral Amyloid in vivo and Persists for More than 72 h Rendering It Suitable for PET/CT Imaging Using 124I Presented at Society of Nuclear Medicine Annual Meeting; 2012 Jun 9-13; Miami Beach, FL.

Osborne D, Stuckey A, Richey T, Kennel S, Wall J. First Characterization of X-Ray Dose in Murine Animals Using the Inveon CT Platform and NanoDot Dosimeters Presented at Society of Nuclear Medicine Annual Meeting; 2012 Jun 9-13; Miami Beach, FL.

Osborne D, Stuckey A, Kennel S, Richey T, Pryer L, Yan S, Wall J. Dose Reduction in Small Animal Imaging Using a Modified Phosphor Screen Presented at Society of Nuclear Medicine Annual Meeting; 2012 Jun 9-13; Miami Beach, FL.

Wall J. Perspectives in Amyloid Imaging Presented at XIIIth International Symposium on Amyloidosis; 2012 May 6-10; Gronigen, Netherlands.

Wall J, Kennel S, Williams A, Richey T, Stuckey A, Huang Y, Donnell R, Barbour R, Seubert R, Solomon A, Schenk D. AL Amyloid Imaging and Therapy with an Amyloid Specific Monoclonal Antibody Presented at XIIIth International Symposium on Amyloidosis; 2012 May 6-10; Gronigen, Netherlands.

Wall J, Williams A, Huang Y, Kennel S. Amyloid Fibrils Possess Characteristic Electronegative Fingerprints that Can Be Distinguished by Poly-Basic Peptides Presented at XIIIth International Symposium on Amyloidosis; 2012 May 6-10; Gronigen, Netherlands.

Wall J, LeBlanc A, Richey T, Stuckey A, Martin E, Macy S, Donnell R, Kennel S. Amyloid-Reactive Peptides Bind MelA+ Melanocytes and Extracellular Melanin in Human, Canine and Murine Melanoma Tumors Presented at XIIIth International Symposium on Amyloidosis; 2012 May 6-10; Gronigen, Netherlands.

Wall J, Richey T, Martin E, Stuckey A, Williams A, Macy S, Kennel S. In vivo Biodistribution of the Amyloid-Reactive Peptide, p5, Correlates with ex vivo Amyloid Quantitation Based on Congo Red Tissue Staining Presented at XIIIth International Symposium on Amyloidosis; 2012 May 6-10; Gronigen, Netherlands.

Wall J,Richey T, Stuckey A, Williams A, Huang Y, Martin E, Sallie Macy, Kennel S. The Novel Polybasic Peptide p5R Can Be Used to Identify Murine and Human Amyloid Deposits in vitro and in vivo Presented at XIIIth International Symposium on Amyloidosis; 2012 May 6-10; Gronigen, Netherlands.

Wells K, Wall J, Kennel S, Solomon A. Radioimmunoimaging in Systemic Light Chain (AL) Amyloidosis Presented at XIIIth International Symposium on Amyloidosis; 2012 May 6-10; Gronigen, Netherlands.

Kennel S, Richey T, Stuckey A, Huang Y,  Akula M, Kabalka G, Martin E, Heidel E, Tigyi G, LeBlanc A, Wall J. Manual Quantitation of B16F10 Pulmonary Tumor Colonies in Mice Correlates with FLT-18 Uptake Presented at World Molecular Imaging Congress; 2011 Sep 7-10; San Diego, CA.

Wall J, LeBlanc A, Richey T, Stuckey A, Akula M, Kabalka G, Martin E, Macy S, Kennel S. In vitro and in vivo Reactivity of Heparin-Binding Peptides with Human and Murine Tumors Presented at World Molecular Imaging Congress; 2011 Sep 7-10; San Diego, CA.

Wall J, Richey T, Stuckey A, Williams A, Huang Y, Martin E, Kennel S. Optimization of a Novel Peptide Tracer for the Detection of Visceral Amyloidosis by Comparative Dual Energy SPECT Imaging Presented at World Molecular Imaging Congress; 2011 Sep 7-10; San Diego, CA.

Wall J, Richey T, Stuckey A, Williams A, Huang Y, Martin E, Macy S, Kennel S. Hypersulfated Heparan Sulfate Glycosaminoglycans - Novel Cerebral and Visceral Amyloid-Associated Biomarkers in Mouse and Man that Can Be Targeted with the Heparin-Binding Peptide p5 Presented at World Molecular Imaging Congress; 2011 Sep 7-10; San Diego, CA.

Martin E, Wall J, Richey T, Stuckey A, Osborne D, Kennel SJ. Stable and Rapid Binding of 124I-labeled Peptide p5 to Visceral Amyloid in vivo as Evidenced by Dynamic PET Imaging Presented at World Molecular Imaging Congress; 2011 Sep 7-10; San Diego, CA.

Martin E, Wall J, Morandi F, Seddighi R,  Doherty T, Long M,  Kojima C, LeBlanc A. Volumetric Quantification of Regional Adiposity in Miniature Swine Using Segmented CT Data Presented at World Molecular Imaging Congress; 2011 Sep 7-10; San Diego, CA.

LeBlanc A, Akula M, Martin E, Rowe J,  Galyon G,  Moyers T, Stuckey A, Long M, Wall J, Kennel S, Kabalka G,  Besozzi M. Whole-Body Biodistribution of 14(R,S)-[18F]Fluoro-6-Thia-Heptadecanoic Acid with Positron Emission Tomography/Computed Tomography (PET/CT) in Domestic Cats Presented at World Molecular Imaging Congress; 2011 Sep 7-10; San Diego, CA.

LeBlanc A, Akula M, Martin E,  Rowe J, Galyon G, Moyers T, Stuckey A, Long M, Wall J, Kennel S, Kabalka G. Whole-body Biodistribution of 3'-deoxy-3'-[18F]fluorothymidine (18FLT) in Normal Adult Cats Presented at World Molecular Imaging Congress; 2011 Sep 7-10; San Diego, CA.

Wall J. Translational Research - From the Micro to the mCT Presented at Siemens Quarterly Communications Meeting; 2011 Aug 17; Knoxville, TN.

Wall J, Richey T, Martin E, Stuckey A, Kennel S. Preclinical Validation of a Novel Peptide Radiotracer for Detecting Amyloidosis Presented at Society of Nuclear Medicine Annual Meeting; 2011 Jun 4-8; San Antonio, TX.

Wall J, Richey T, Martin E, Stuckey A, Kennel S. The 99mTc-p31 Peptide Offers Enhanced Amyloid Imaging as Compared to SAP A Quantitative Biodistribution and Dual Energy SPECT Imaging Study Presented at Society of Nuclear Medicine Annual Meeting; 2011 Jun 4-8; San Antonio, TX.

Wall J, Richey T, Martin E, Stuckey A, Kennel S. Biodistribution of Amyloid-Imaging Peptide, P31, Correlates with Amyloid Quantitation Based on Congo Red Tissue Staining Presented at Society of Nuclear Medicine Annual Meeting; 2011 Jun 4-8; San Antonio, TX.

Wells K, Wall J, Kennel S,  Jakoby B,  Solomon A. Radioimmunoimaging of Cardiac Amyloid Deposits in AL Amyloidosis Patients Presented at The Society of Nuclear Medicine Annual Meeting; 2011 Jun 4-8; San Antonio, TX.

Wall J. The role Inveon SPECT Imaging Plays in Translational Research Presented at World Molecular Imaging Congress; 2010 Sep 8-11; Kyoto, Japan.

Wall J. Imaging Amyloidosis: A Case Study in Translational Research Covering Preclinical Discovery and Validation of Novel Diagnostic and Therapeutic Agents Presented at World Molecular Imaging Congress; 2010 Sep 8-11; Kyoto, Japan.

Wall J. Molecular Imaging: Technology, Tracers and Translation Presented at Annual Scientific Conference of the American College of Veterinary Radiology; 2010 Aug 15-19; Asheville, NC.

Wall J, Stuckey A, Kennel S, Richey T, Morandi F, Jones M, Greenacre C, Souza M,  LeBlanc A. Diagnostic Veterinary Imaging Using Micro-Imaging Platforms Presented at Annual Scientific Conference of the American College of Veterinary Radiology; 2010 Aug 15-19; Asheville, NC.

Wall J. Research in Noninvasive Imaging for Amyloidosis Lecture Presented at ORNL Measurement Science and Systems Engineering Distinguished Lecture Series; 2010 Jul; Oak Ridge, TN.

Wall J. Radioimmunoimaging of AL Amyloidosis Presented at Society of Nuclear Medicine Annual Meeting; 2010 Jun 5-9; Salt Lake City, UT.

Wall JS,  Richey T, Stuckey A, Donnell R, Martin E, Solomon A, Kennel SJ. Imaging the Biodistribution of Systemic AA Amyloidosis in Mice Using 125I-Labeled Protamine Presented at Society of Nuclear Medicine Annual Meeting; 2010 Jun 5-9; Salt Lake City, UT.

Wall J, Kennel S, Stuckey A, Townsend DW,  Wells K, Stabin M, Solomon A. The Fibril-Reactive Antibody 11-1F4 Co-localizes with Amyloid in Patients with AL Amyloidosis Presented at XII International Symposium on Amyloidosis; 2010 Apr 18-21; Rome, Italy.

Wall J,  Richey T, Stuckey A, Donnell R,  Martin E, Solomon A, Kennel S. 125I-labeled, Heparin-Reactive Protamine (and other peptides) as a Novel Amyloid Imaging Reagents Presented at XII International Symposium on Amyloidosis; 2010 Apr 18-21; Rome, Italy.

Wall J,  Richey T,  Hawkins P, Solomon A,  Kennel S. 99mTc-Labeled Serum Amyloid P Component as a Tool for Evaluating Novel Amyloid Imaging Agents Presented at XII International Symposium on Amyloidosis; 2010 Apr 18-21; Rome, Italy.

Wall J, Richey T, Stuckey A,  Seubert P, Barbour R, Schenk D, Solomon A, Kennel S. Immunoimaging of AA Amyloid Using a Novel Amyloid-Specific Tracer Presented at XII International Symposium on Amyloidosis; 2010 Apr 18-21; Rome, Italy.

Wall J,  Richey T, Stuckey A, Solomon A,  Kennel S. Rapid Dehalogenation of 124I-SAP in Mice Enhances the Specific Detection of Amyloid: A Dynamic microPET Imaging Study Presented at XII International Symposium on Amyloidosis; 2010 Apr 18-21; Rome, Italy.

Wall J,  Richey T,  Stuckey A,   Kennel S,  Solomon A. Quantitative Analysis of Amyloid Mass in Mice by Image Segmentation Presented at XII International Symposium on Amyloidosis; 2010 Apr 18-21; Rome, Italy.

Stuckey A, Wall J, Kennel S, Richey T, Solomon A,  Long M,  Watson D,  Gildrich R, Powell M, Wells K, Love T, Hines B, Smith G, Townsend D. Clinical Translation of a Therapeutic Antibody: From Mouse to Man Presented at Tennessee Society of Nuclear Medicine Technologists; 2010 Apr 9-11; Chattanooga, TN.

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