The University of Tennessee Graduate School of Medicine, Knoxville

The Department of Pathology

Amila Orucevic, MD, PhD


Clinical Focus

Surgical Pathology, Gastrointestinal Pathology, Gynecologic Pathology

Research Focus

Dr. Orucevic's research is focused on the development of practical statistical models designed to predict prognosis of patients with breast cancer that can be used in the therapeutic decision making process. Working with Dr. Heidel, she is developing calculators that can predict breast cancer genomic test results, such as Oncotype DX and Mammaprint, without performing the tests themselves. These tests are expensive (~$4,000) and are not affordable for the majority of patients worldwide. They are utilized in ~30% of eligible breast cancer patients in the USA but play an important role as "precision medicine."

Her recently published calculator for prediction of Oncotype DX test results is widely used. The research paper describing the calculator was the most downloaded publication for the "Breast Cancer Research and Treatment" journal in 2017.


Medical School
University of Sarajevo Medical School, Bosnia and Herzegovina, 1978-1983

Anatomic and Clinical Pathology, Rush University Medical Center, Chicago, IL,1998-2002

Surgical Pathology, Loyola University Medical Center, Maywood, IL, 2002-2003


The Royal College of Physicians and Surgeons of Canada in Anatomic Pathology, 2002
The American Board of Pathology in Combined Anatomic Pathology and Clinical Pathology, 2002

Current Publications

Scheiderer A, Riedinger C, Kimball K, Kilgore L, Orucevic A.
Reporting subclonal immunohistochemical staining of mismatch repair proteins in endometrial carcinoma in the times of ever-changing guidelines. Arch Pathol Lab Med. 2022 Sep 1;146(9):1114-1121. doi: 10.5858/arpa.2021-0201-OA.

Cochrane K, Bell JL, Heidel RE, Orucevic A.
Adenosquamous carcinoma of the breast, an uncommon diagnosis with poor prognosis-Lessons learned from a 12-year analysis of the National Cancer Database. The Breast Journal. 2021 Feb;27(2):165-169. Epub 2021 Jan 22.

Current Presentations

Hurley MS, Baker M, Reed R, Orucevic A, Lewis J, Kilgore L, Young Y. Rare presentation of primary mucinous adenocarcinoma, mammary type of the vulva Presented at SoutEastern Surgical Congress 2023 Annual Meeting ; 2023 Feburary - 11; Savannah.

Bach KM, Orucevic A, Duncan LD. Case Study of Low-Grade Mucinous Carcinoma Peritonei Metastatic to an Axillary Lymph Node. Presented at 2022 College of American Pathologists Annual Meeting; 2022 October-8; New Orleans, Louisiana.

Vagaiwalla K, Enomoto L, Esantis, Faulkner N, Orucevic A. Diagnosis of sarcomatoid adrenal cortical carcinoma in the era of personalized medicine. Presented at College of American Pathologists Meeting, Annual 2022 meeting; 2022 October-11; New Orleans, LA.


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