Anesthesia Research Facility
Roger C. Carroll, PhD
Professor and Director
Carolyn Snider
Medical Technologist
Current Areas of Research Interest
- Development and testing of clinical assays using the Thrombelastograph to measure platelet function and blood coagulation/anticoagulation. These clinical assays include the monitoring of aspirin, Plavix and other anti-coagulant therapies in cardiology patients, anti-coagulant therapies in thrombophilic pregnancy and other patient populations, post-traumatic hemostatic changes, and hemostatic changes associated with cardiopulmonary bypass.
- Testing new strategies to minimize post-operative pain and nausea. These innovative approaches include traditional pharmaceutical and complementary acupuncture/electrical stimulation techniques.
- Assessing safer and more effective anesthesia practices for caesarian section, endoscopy/colonoscopy procedures and chronic pain management.
- Development of Positron Emission Tomography neuroreceptor probes to measure specific interactions of anesthesia agents with targets in the brain controlling consciousness.
Publications
Carroll, R.C., Owers, R.L., Elder, R.F., Hennessey, M.D., Patteson, S.K., Snider, C.C., Hammer, N.L., Quinn, M.P., Muenchen, R.A: Prospective evaluation of platelet B2 bradykinin and thrombopoietin receptor levels from preeclamptic compared to non-preeclamptic pregnancy patients. Thrombosis Research 117: 551-556, 2006.
Carroll, R.C., Chavez, J.J., Simmons, J.W., Snider, C.C., Wortham , D.C., Bresee, S.J., Cohen, E.: Measurement of patients' bivalirudin plasma levels by a Thrombelastograph ecarin clotting time assay. Comparison to a standard activated clotting time. Anesthesia & Analgesia 102: 1316-1319, 2006.
Carroll, R.C., Chavez, J.J., Snider, C.C., Meyer, D.S. Muenchen, R.A.: Correlation of perioperative platelet function and coagulation tests with bleeding after cardiopulmonary bypass surgery. Journal of Laboratory and Clinical Medicine 147: 197-204, 2006.
Connors, S. L., Matteson, K.J., Sega, G., Lozzio, C.B., Carroll, R.C., Zimmerman, A.W.: Plasma serotonin in autism. Pediatric Neurology 35: 182-186, 2006.
Patteson, S.K., Snider, C.C., Meyer, D.S., Enderson, B.L., Armstrong, J.E., Whitaker, G.L., Carroll, R.C.: The consequences of high risk behaviors: Trauma during pregnancy. Journal of Trauma 62:1015-1020, 2007.
Carroll, R.C., Craft, R.M., Whitaker, G.L., Snider, C.C., Kirby, R.K., Elder, R.F., Hennessey, M.D Thrombelastography monitoring of resistance to enoxaparin anticoagulation in thrombophilic pregnancy patients. Thrombosis Research (in press 2007).
ABSTRACTS:
Patteson, SK, Snider, CC, Meyer, DS, Fronczek, E., Scott, J, Carroll, RC: A Comparison of Acupoint Electrical Stimulation ReliefBand Versus Low Dose Granisetron or Dolasetron for Preventing Postoperative Nausea and Vomiting in Women Undergoing Laparoscopic Surgery” (Control # 1169) IARS 80th Clinical and Scientific Congress, San Francisco, 2006.
The Effect of a Structured Introductory Reading Program on Anesthesia Knowledge Test (AKT) Scores at The University of Tennessee Graduate School of Medicine. Daniel R. Bustamante, M.D.; Brian R. Conroy, M.D.; Roger C. Carroll, PhD; Robert M. Craft, M.D. SEA Meeting Nashville TN, 2006
The Effect of an Introductory Reading Program and a Board Review Series on In-Training Exam-1 Scores. Daniel R. Bustamante, M.D., Kip D. Robinson, M.D., Roger C. Carroll, Ph.D. ASA Oct. 2006 A1327.
Tight glycemic control with continuous insulin infusion during cardiopulmonary bypass. Jack J. Chavez, M.D., ABA , Brian R. Conroy, M.D., Carolyn C. Snider, M.T., Ryan K. Kirby, B.S, Roger C. Carroll, Ph.D. (Abstract Number 17) SCA Annual Meeting, April 21-25, 2007, Montreal, Quebec , Canada .
The University of Tennessee Graduate School of Medicine
Department of Anesthesiology
1924 Alcoa Highway, U-109
Knoxville, TN 37920
Phone: (865)-305-9220