The University of Tennessee Graduate School of Medicine, Knoxville



The Department of Radiology

Dustin R. Osborne, PhD

Associate Professor
Molecular Imaging and Translational Research Program

Education

Graduate School
Ph.D., Nuclear Engineering, University of Tennessee, 2006-2011
M.S., Physics: Medical Imaging Physics, University of Tennessee, Knoxville, TN, 2003-2005

Internship
Graduate Research, CITDP, Univeristy of Tennessee Graduate School of Medicine, 2004 - 2006

Certifications

American Board of Nuclear Science in Medicine: Nuclear Medicine Physics & Instrumentation
American Board of Radiology: Board Eligible

Awards and Honors

Selected for and graduated from prestigious Siemens Learning Campus 20-month leadership program
2012 Society of Nuclear Medicine Poster Award Nominee: Honorable Mention
2014 Society of Nuclear Medicine and Molecular Imaging Computer and Instrumentation Council Young Investigator Award

Professional Affiliations

Society of Nuclear Medicine
International Electrical and Electronics Engineers

Current Publications

Osborne DR, Kuntner C, Berr S, Stout D.
Guidance for efficient small animal imaging quality control. Molecular Imaging and Biology. 2016 Oct 13. [Epub ahead of print]

Acuff S, Osborne DR.
Clinical workflow considerations for implementation of continuous bed motion PET/CT. Journal of Nuclear Medicine Technology. 2016 Jun;44(2):55-8. Epub 2016 Apr 21.

Osborne DR, Acuff S.
Whole-body dynamic imaging with continuous bed motion PET/CT. Nuclear Medicine Communications. 2016 Apr;37(4):428-31. Epub 2015 Dec 1.

van der Vos CS, Grootjans W, Osborne DR, Meeuwis AP, Hamill J, Acuff S, de Geus-Oei LF, Visser EP.
Improving the spatial alignment in PET/CT using amplitude-based respiratory gated PET and respiratory triggered CT. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 2015 Dec;56(12):1817-22. Epub 2015 Sep 17.

Osborne DR , Austin DW.
Feasibility and initial performance of simultaneous SPECT-CT imaging using a commercial multi-modality preclinical imaging system. International Journal of Molecular Imaging. 2015;2015:134768.

Osborne DR, Acuff SN, Stuckey A, Wall JS.
A routine PET/CT protocol with streamlined calculations for assessing cardiac amyloidosis using 18F-Florbetapir. Frontiers in Cardiovascular Medicine. Front Cardiovasc Med. 2015 May 2:23.

Lee S, Gregor J, Kennel SJ, Osborne DR, Wall J.
GATE validation of standard dual energy corrections in small animal SPECT-CT. Plos One . 2015 Apr 7;10(4):e0122780.

Osborne DR, Acuff S, Cruise S, Syed M, Neveu M, Stuckey A, Bradley Y.
Quantitative and qualitative comparison of continuous bed motion and traditional step and shoot PET/CT. American Journal of Nuclear Medicine and Molecular Imaging . 2014 Dec 15;5(1):56-64.

Martin EB, Kennel SJ, Richey T, Wooliver C, Osborne D, Williams A, Stuckey A, Wall JS.
Dynamic PET and SPECT imaging with radioiodinated, amyloid-reactive peptide p5 in mice: A positive role for peptide dehalogenation. Peptides. 2014 Oct;60:63-70.

Acuff SN, Bradley YC, Barlow P, Osborne DR.
Reduction of patient anxiety in PET/CT imaging by improving communication between patient and technologist. Journal of Nuclear Medicine Technology. 2014 Sep;42(3):211-7.

Williams LM, Morandi F, Osborne DR, Narak J, LeBlanc AK.
Kinetic analysis of 2-([(18)F]fluoro)-2-deoxy-d-glucose uptake in brains of anesthetized healthy dogs. American Journal of Veterinary Research . 2014 Jun;75(6):588-94.

Pasciak AS, Bourgeois AC, McKinney JM, Chang TT, Osborne DR, Acuff SN, Bradley YC.
Radioembolization and the dynamic role of Y PET/CT. Frontiers in Oncology . 2014 Feb 27;4:38. eCollection 2014.

Current Presentations

Oler PR, Brown SJ, Campbell PD, Ferrell AS, Fox DR, Osborne DR. Reproducible MRI and radiographic criteria for grading cervical facet and disc degeneration. Presented at International Skeletal Society 43rd Annual Meeting; 2016 Sep 6-9; Paris, France.

Osborne D, Acuff S, Kaman A, Fu Y. Impact of amplitude-based gating on Y90 PET/CT diagnostic interpretation. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

Osborne D, Acuff S. A novel method for whole-body dynamic imaging using continuous bed motion PET/CT with non-invasive estimation of arterial input function using an external radiation detector device. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

Osborne D, Acuff S, Gregor J, Goddard J. Real-time motion correction using high resolution: High frame rate video monitoring and 64-bit list mode event repositioning. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

Acuff S, Whittle B, Osborne D. Comparison of workflow efficiency and technologist radiation exposure when using TheraSphere and SIR-Sphere Y90 microspheres for liver cancer therapy. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

Acuff S, Jackson A, Osborne D. Clinical considerations for using PET/CT in radiation therapy. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

Akula M, Blevins D, Kabalka G, Osborne D. Continuous flow microfluidic chemistry: Synthesis of [F-18]Fluoro analogues of aniracetam as brain imaging agents. Presented at 250 th Annual Meeting of the American Chemical Chemistry; 2015 Aug 16-20; Boston, MA.

Acuff S, Bradley Y, Stuckey A, Osborne D. Routine PET/CT workflow efficiency and scan time improvements using continuous bed motion (CBM) techniques. Presented at Society of Nuclear Medicine and Molecular Imaging Annual Meeting; 2015 Jun 6-10; Baltimore, MD.

Osborne D, Lee S, Hu D, Acuff S. Head and neck motion correction in PET imaging using new particle tracking techniques. Presented at Society of Nuclear Medicine and Molecular Imaging Annual Meeting; 2015 Jun 6-10; Baltimore, MD.

Osborne D, Stuckey A, Kennel S, Blevins D, Akula M. Fluroaniracetam: Initial biodistribution and characterization of a new brain imaging agent. Presented at Society of Nuclear Medicine and Molecular Imaging Annual Meeting; 2015 Jun 6-10; Baltimore, MD.

Acuff S, Osborne D. Non-invasive input function measurement using a modular detector device. Presented at Society of Nuclear Medicine and Molecular Imaging Annual Meeting; 2015 Jun 6-10; Baltimore, MD.

Acuff S, Bradley Y, Stuckey A, Osborne D. PET/CT gating workflow efficiency improvements using continuous bed motion imaging techniques. Presented at Society of Nuclear Medicine and Molecular Imaging Annual Meeting; 2015 Jun 6-10; Baltimore, MD.

Martin E, Richey T, Stuckey A, Macy S, Wooliver C, Osborne D, Kennel S, Wall J. Non-invasive detection of critical cardiac amyloid deposits using a novel peptide, p5R+14. Presented at 24th American Peptide Symposium; 2015 Jun 20-25; Orlando, FL.

Akula M, Blevins D, Kabalka G, Osborne D. Synthesis of a new thiol reactive bifunctional agent [18F]FPyAM using microfluidic system. Presented at The 21st International Symposium on Radiopharmaceutical Sciences; 2015 May 26-31; Columbia, MO.

Akula M, Blevins D, Kabalka G, Osborne D. Synthesis of N-[4-(2’-[18F]fluoroethyloxybenzoyl)]pyrrolidin-2-one: A potential new brain imaging agent. Presented at The 21st International Symposium on Radiopharmaceutical Sciences; 2015 May 26-31; Columbia, MO.

Akula M, Blevins D, Kabalka G, Osborne D. Synthesis of [123I]Iodoaniracetam, a SPECT agent for brain imaging. Presented at The 21st International Symposium on Radiopharmaceutical Sciences; 2015 May 26-31; Columbia, MO.

Akula M, Blevins D, Kabalka G, Osborne D. Microfluidic Synthesis of N-[6-(4-[18F]fluorobenzylidine)aminooxyhexyl]maleimide. Presented at The 21st International Symposium on Radiopharmaceutical Sciences; 2015 May 26-31; Columbia, MO.

Acuff S, Osborne D. Use of optimal respiratory gating with continuous bed motion PET/CT to improve personalized radiation therapy planning. Presented at Radiological Society of North America; 2014 Nov 30 - Dec 5; Chicago, IL.

Osborne D. PET/CT imaging using continuous bed motion. Presented at European Association of Nuclear Medicine; 2014 Oct 18-22; Gothenburg, Sweden.

Martin EB, Richey T, Stuckey A, Wooliver C, Macy S, Osborne D, Kennel SJ, Wall JS. Detection of cardiac amyloidosis by SPECT/CT imaging using both 125I-serum amyloid P-component and the novel 125I- p5R+14 peptide. Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

Martin EB, Richey T, Stuckey A, Heidel RE, Lee A, Rader B, Osborne D, Kennel SJ, Wall JS. Characterization of peptide 125I-p5R+14 as an optimized radiotracer for the in vivo detection of ApoA2c amyloidosis. Presented at XIVth International Symposium on Amyloidosis; 2014 Apr 27 - May 1; Indianapolis, IN.

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