The University of Tennessee Graduate School of Medicine, Knoxville



The Department of Radiology

Dustin R. Osborne, PhD

Associate Professor
Molecular Imaging and Translational Research Program

Education

Graduate School
Ph.D., Nuclear Engineering, University of Tennessee, 2006-2011
M.S., Physics: Medical Imaging Physics, University of Tennessee, Knoxville, TN, 2003-2005

Internship
Graduate Research, CITDP, Univeristy of Tennessee Graduate School of Medicine, 2004 - 2006

Certifications

American Board of Nuclear Science in Medicine: Nuclear Medicine Physics & Instrumentation
American Board of Radiology: Board Eligible

Awards and Honors

Selected for and graduated from prestigious Siemens Learning Campus 20-month leadership program
2012 Society of Nuclear Medicine Poster Award Nominee: Honorable Mention
2014 Society of Nuclear Medicine and Molecular Imaging Computer and Instrumentation Council Young Investigator Award

Professional Affiliations

Society of Nuclear Medicine
International Electrical and Electronics Engineers

Current Publications

Rowe JA, Morandi F, Osborne DR, Wall JS, Kennel SJ, Reed RB, LeBlanc AK.
Relative skeletal distribution of proliferating marrow in the adult dog determined using 3'-deoxy-3'-[(18) F]fluorothymidine. Anatomia, Histologia, Embryologia. 2018 Oct 23. [Epub ahead of print]

Acuff SN, Jackson AS, Subramaniam RM, Osborne DR.
Practical consideration for integrating PET/CT in radiation therapy planning for patient care. Journal of Nuclear Medicine Technology. 2018 Aug 3. [Epub ahead of print]

Akula MR, Blevins D, Kabalka GW, Osborne D.
Synthesis of N-[4-(2'-[18F]fluoroalkyloxybenzoyl)]- and N-[4-methoxy-3[123I]iodobenzoyl]-pyrrolidin-2-ones as potential brain imaging agents. Heterocycles. 2018 Jun 12;97. [Epub ahead of print]

Blevins DW, Kabalka GW, Osborne DR, Akula MR.
Effect of added Cu(OTf)2 on the Cu(OTf)2(Py)4-mediated radiofluorination of benzoyl and phthaloylglycinates. Natural Science. 2018 Mar;10(3):83524.

Osborne DR, Acuff SN, Neveu ML, Syed M, Kaman AD, Fu Y.
Feasibility assessment of yttrium-90 liver radioembolization imaging using amplitude-based gated PET/CT. Nuclear Medicine Communications. 2018 Mar;39(3):222-227.

Osborne DR, Kuntner C, Berr S, Stout D.
Guidance for efficient small animal imaging quality control. Molecular Imaging and Biology. 2017 Aug;19(4):485-498.

Osborne DR, Acuff S, Neveu M, Kaman A, Syed M, Fu Y.
90 Y liver radioembolization imaging using amplitude-based gated PET/CT. Clinical Nuclear Medicine. 2017 May;42(5):373-374. Epub 2017 Feb 24.

Acuff S, Osborne DR.
Clinical workflow considerations for implementation of continuous bed motion PET/CT. Journal of Nuclear Medicine Technology. 2016 Jun;44(2):55-8. Epub 2016 Apr 21.

Osborne DR, Acuff S.
Whole-body dynamic imaging with continuous bed motion PET/CT. Nuclear Medicine Communications. 2016 Apr;37(4):428-31. Epub 2015 Dec 1.

van der Vos CS, Grootjans W, Osborne DR, Meeuwis AP, Hamill J, Acuff S, de Geus-Oei LF, Visser EP.
Improving the spatial alignment in PET/CT using amplitude-based respiratory gated PET and respiratory triggered CT. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 2015 Dec;56(12):1817-22. Epub 2015 Sep 17.

Current Presentations

Acuff S, Whittle B, Green C, Findeiss L, Taylor R, Leschak S, Stephens C, Osborne D. Comparison of interventioonal radiologist and the nuclear medicine technologist radiation exposure when using TheraSphere and SIR-Spheres for liver cancer therapy. Presented at Society of Nuclear Medicine and Molecular imaging; 2017 Jun 10-14; Denver, CO.

Osborne DR. Emerging technologies in PET/CT. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2017 Jun 10-14; Denver, CO.

Osborne DR. Emerging technologies in preclinical and translational imaging. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2017 Jun 10-14; Denver, CO.

Osborne D, Acuff S, Green C, Taylor R, Findeiss L, Stephens C. Real-time monitoring of yttrium 90 radioembolization dose delivery. Presented at Society of Nuclear Medicine and Molecular Imaging; 2017 Jun 10-14; Denver, CO.

Osborne D, Acuff S, Tumpa T, Hu D. Respiratory motion correction using novel particle tracking techniques. Presented at Society of Nuclear Medicine and Molecular Imaging; 2017 Jun 10-14; Denver, CO.

Fang M, Acuff S, Osborne DR. Use of thermal imaging for respiratory motion correction in PET/CT. Presented at Society of Nuclear Medicine and Molecular Imaging; 2017 Jun 10-14; Denver, CO.

Acuff S, Gaston C, Osborne D. Use of thermal imaging to intervene in brown fat activation prior to PET/CT imaging. Presented at Society of Nuclear Medicine and Molecular imaging; 2017 Jun 10-14; Denver, CO.

Akula M, Blevins D, Kabalka G, Osborne D. Microfluidic synthesis of aniracetam analogues as potential PET brain imaging agents. Presented at International Symposium on Radiopharmaceutical Sciences (Invited Lecture); 2017 May 14-19; Dresden, Germany.

Blevins D, Akula M, Kabalka G, Osborne D. Synthesis of 4-(4-[18F]fluorophenylpiracetam, a potential PET agent for Parkinson’s disease. Presented at International Symposium on Radiopharmaceutical Sciences (Invited Lecture); 2017 May 14-19; Dresden, Germany.

Akula M, Blevins D, Kabalka G, Osborne D. Improved Microfluidic Synthesis of 1-(2-[18F]fluoroethoxy)-4-[2-{4-(methylsulfonyl) phenyl}cyclopent-1-enyl]benzene, a potential COX-2 inhibitor to characterize solid tumors. Presented at International Symposium on Radiopharmaceutical Sciences (Invited Lecture); 2017 May 14-19; Dresden, Germany.

Oler PR, Brown SJ, Campbell PD, Ferrell AS, Fox DR, Osborne DR. Reproducible MRI and radiographic criteria for grading cervical facet and disc degeneration. Presented at International Skeletal Society 43rd Annual Meeting; 2016 Sep 6-9; Paris, France.

Osborne D, Acuff S, Kaman A, Fu Y. Impact of amplitude-based gating on Y90 PET/CT diagnostic interpretation. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

Osborne D, Acuff S. A novel method for whole-body dynamic imaging using continuous bed motion PET/CT with non-invasive estimation of arterial input function using an external radiation detector device. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

Osborne D, Acuff S, Gregor J, Goddard J. Real-time motion correction using high resolution: High frame rate video monitoring and 64-bit list mode event repositioning. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

Acuff S, Whittle B, Osborne D. Comparison of workflow efficiency and technologist radiation exposure when using TheraSphere and SIR-Sphere Y90 microspheres for liver cancer therapy. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

Acuff S, Jackson A, Osborne D. Clinical considerations for using PET/CT in radiation therapy. Presented at Society of Nuclear Medicine and Molecular Imaging (Invited Lecture); 2016 Jun 11-15; San Diego, CA.

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