The University of Tennessee Graduate School of Medicine, Knoxville



The Department of Surgery

James M. McLoughlin, MD, FACS

Professor
Division of Surgical Oncology

Research Focus

Dr. McLoughlin, in collaboration with Dr. Kelley, is studying the relationship between the microbiome of the oral cavity, lung bronchi and colon, and predictors of successful treatment with immunotherapy used in lung cancer treatment. Additionally, research is focused on the evaluation of post-surgery acute pain pathways and viability of narcotic-free colon resection.

Education

Medical School
Rush University Medical School

Internship
Baylor University Medical Center

Residency
Baylor University Medical Center

Fellowship
H. Lee Moffitt Cancer Center

Certification

American Board of Surgery

Professional Affiliations

New Member Committee, Society of Surgical Oncology 2008 - present
Member, Association of Academic Surgeons 2008 - present
Member, Society of Baylor Surgeons 2001 - present
Member, American College of Surgeons 2002 - present
Member, American Medical Association 2004 - present
Member, Florida Medical Association 2006 - present
Member, Society of Surgical Oncology 2007 - present
Member, Georgia Medical Association 2007 - present
Member, Georgia Chapter of the American College of Surgeons 2007 - present
Member, Association for Academic Surgery 2008 - present
Member, Society of Surgical Educators 2009 – present
Association of Academic Surgeons, Ethics Committee 2008 – present
Society of Surgical Oncology, New Members Committee 2008 – present
Department of Defense, Breast Cancer Grant Review Committee 2009 – present
Association of Academic Surgeons, New Members Committee 2011 – present


Current Publications

Schmocker RK, Enomoto LM, Low GK, McLoughlin JM, Casillas MA Jr, Antill AC, Heidel RE, Russ AJ.
Further distance from treating facility is associated with advanced colon cancer at presentation and increased mortality. Am Surg. 2024 Mar 29:31348241241613. doi: 10.1177/00031348241241613. Online ahead of print.

Schmocker RK, Gray KD, Eric Heidel R, Vanterpool SG, McLoughlin JM..
A novel preoperative patient survey predicts adverse patient outcomes-implementation and preliminary results of the tennessee preoperative assessment tool. Am Surg. 2023 Jul;89(7):3192-3199. doi: 10.1177/00031348231157848. Epub 2023 Feb 28.

Brown S, McLoughlin J, Russ A, Casillas M, Buehler J, Heidel RE, Yates JR.
Alvimopan retains efficacy in patients undergoing colorectal surgery within an established ERAS program. Surg Endosc. 2022 Aug;36(8):6129-6137. doi: 10.1007/s00464-021-08928-7. Epub 2022 Jan 18.

Brown S, McLoughlin J, Russ A, Casillas M, Buehler J, Heidel RE, Yates JR.
Alvimopan retains efficacy in patients undergoing colorectal surgery within an established ERAS program. Surg Endosc. 2022 Aug;36(8):6129-6137. doi: 10.1007/s00464-021-08928-7. Epub 2022 Jan 18.

Arroyave AJ, Lewis JM, Landry M, McLoughlin JM, Enomoto LM.
Merkel cell polyomavirus antibody titer predicts recurrence-free survival. Ann Surg Oncol. 2022 Mar;29(3):1620-1626. doi: 10.1245/s10434-021-11008-8. Epub 2021 Dec 1.

Arroyave AJ, Lewis JM, Landry M, McLoughlin JM, Enomoto LM.
Merkel cell polyomavirus antibody titer predicts recurrence-free survival. Ann Surg Oncol. 2022 Mar;29(3):1620-1626. doi: 10.1245/s10434-021-11008-8. Epub 2021 Dec 1.

Current Presentations

B Humphreys, AJ Russ, R Schmocker, GS Onar, T Henderson, J McLoughlin, G Low. Outcomes in colorectal surgery comparing intravenous lidocaine, quadratus lumborum (QL) block, and tranversus abdominis plane (tap) blocks. Presented at American Society of Colon & Rectal Surgeons; 2024 June - 1; Baltimore, MD.

Balmer JC, Walker MG, McLoughlin JM, Schmocker RK. Combined endoscopic-laparoscopic pancreatic cystogastrostomy for a hostile abdomen Presented at Tennessee Chapter of American College of Surgeons; 2023 July-27; Spencer, TN .

Ward A, McLoughlin J, Campbell E. Novel Ways to Expand Genomics Services: How We Do It. Presented at 2022 CGA-IGC / 26th Annual Meeting; 2022 November-12; Nashville, TN.

Jong J, Russ A, Martin, McLoughlin J, Casillas M. Robotic Versus Laparoscopic Low Anterior Resection for Rectosigmoid Adenocarcinoma: A Single-center experience. Presented at 2022 Annual Residents’ Research Day; 2022 June-10; Knoxville, TN.

Park B, Kim Ji Y, Riffey O, Bruckbauer A, McLoughlin J, Bettaieb A, Donohoe D. Pyruvate Kinase M1 Regulates Butyrate Metabolism in Cancerous Colonocytes. Presented at Experimental Biology 2022 / APS Gastrointestinal cancer and metastasis; 2022 April-2; Philadelphia, PA.

Arroyave AJ, Good AW, McLoughlin JM, Casillas MA, Heidel RE, Russ AJ. Disparities in presentation and treatment of colon cancer between rural and metropolitan communities. Presented at Tennessee Chapter of the American College of Surgeons; 2021 Aug 6-8; Memphis, TN.

Antill AC, Lewis RE, Taylor JE, Daley BJ, McLoughlin JM, Casillas MA, Russ AJ. Effect of enhanced recovery after surgery protocol implementation on colectomy cost and length of stay: Open vs minimally invasive approach. Presented at Tennessee Chapter of the American College of Surgeons; 2021 Aug 6-8; Memphis, TN.

Arroyave AJ, Antill AC, Schmocker RK, McLoughlin JM, Casillas MA, Heidel RE, Russ AJ. Racial disparities lead to differences in presentation of colon cancer in rural southeast region. Presented at Tennessee Chapter of the American College of Surgeons; 2021 Aug 6-8; Memphis, TN.

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