The Department of Surgery

Oscar H. Grandas, MD, FACS

Professor
Chief, Division of Transplant Surgery
Division of Vascular & Endovascular Surgery
Division of Transplant Surgery

Clinical Focus

Vascular Surgery, Dialysis Access, Kidney Transplantation

Research Focus

The Vascular Research Laboratory performs research investigating the development of intimal hyperplasia and restenosis, the most common chronic complications following balloon angioplasty, vascular stenting, and vascular bypass graft surgery. Significant efforts are focused on designing nanoparticles for targeted vascular drug delivery aimed at hyperplasia prevention. The lab's primary objective is the development of therapeutic interventions to increase the success of endovascular procedures and improve long-term vascular surgical outcomes.

Education

Postgraduate
Master's of Business Administration, Heller School of Management, Brandeis University, Boston, MA

Medical School
Universidad Nacional de Colombia, Bogota, Colombia

Internship
General Surgery, Washington Hospital Center, Washington, DC

Residency
General Surgery, University of Tennessee Graduate School of Medicine

Fellowship
Vascular Surgery, University of Tennessee Graduate School of Medicine
Transplant Surgery, Washington Hospital Center, Washington, DC

Certifications

American Board of Surgery
American Board of Surgery/Vascular Surgery

Professional Affiliations

American College of Surgeons
Southeastern Surgical Congress
The Transplant Society
Association for Academic Surgery
American Society of Transplantation
The Southern Association for Vascular Surgery
Tennessee Transplant Society
American Society of Transplant Surgeons
American College of Physician Executives
Society of Vascular Surgeons

Current Publications

Goldman MP, Patel DM, Chang KZ, Davis RP, Edwards MS, Hurie JB, Sutsrim A, Velazquez-Ramirez G, Williams TK, Grandas OH, Freeman MB, McNally MM, Stevens SL, et. al..
Challenges and potential solutions to enrollment in a clinical trial of arteriovenous fistula vs arteriovenous graft vascular access strategy. JVS Vasc Insights. 2024;2:100108. doi: 10.1016/j.jvsvi.2024.100108. Epub 2024 Jun 7.

Current Presentations

Kinnear T, McAdams C, West PC, Matter-Schain S, Kirkpatrick S, Arnold J, Buckley RM, Freeman M, Grandas O, McNally M, Stevens S, Mountain DJ. Multi-functionalized lipid nanoparticles for targeted delivery in an in vivo model of vascular injury Presented at 18th Annual Academic Surgical Congress; 2023 Feburary - 7; Houston.

Fowler BB, Oliva CD, Arnold JD, Buckley MR, Grandas OH, Goldman MH, Stevens SL, Freeman MB, McNally MM. Outcomes of Critically Ill COVID Positive Patients with Cardiovascular Events. Presented at Tennessee Chapter of the American College of Surgeons; 2022 August-11; Nashville, Tennessee.

West PC, Kinnear TW, Mattern-Schain SI, Kirkpatrick SS, Arnold JD, Buckley MR, Freeman MB, Grandas OH, McNally MM, Mountain DJH. Assembly of Non-Cationic Lipid Nanoparticles for Optimized RNA Drug Payload and Efficacy. Presented at Controlled Release Society 2022 Annual Meeting; 2022 July-11; Montreal, Canada.

McAdams CD, Grimsley LB, West PC, Arnold JD, Buckley RM, Dieter RA, Freeman MB, Grandas OH, McNally MM, Stevens SL. Lipid Nanoparticles Functionalized for Sub-Endothelial Matrix Targeting in Lower Extremity Vessels. Presented at Academic Surgical Congress 2022; 2022 February-1; Orlando, Florida.

Grimsely L, West P, Arnold J, Buckley R, Dieter R, Freeman M, Grandas O, McNally M, Stevens S, Mountain D. Lipid Nanoparticles Functionlized for Sub-Endothelial Matrix Targeting in Lower Extremity Vessels. Presented at Academic Surgical Congress ; 2022 February-1; Orlando, Florida.