The University of Tennessee Graduate School of Medicine, Knoxville



The Department of Surgery

Oscar H. Grandas, MD

Professor
Chief, Division of Transplant Surgery
Division of Vascular & Endovascular Surgery
Division of Transplant Surgery

Clinical Focus

Vascular Surgery, Dialysis Access, Kidney Transplantation, Pancreas Transplantation

Research Focus

Hormone Replacement, Intimal Hyperplasia

Education

Medical School
Universidad Nacional de Colombia, Bogota, Colombia

Internship
General Surgery, Washington Hospital Center, Washington, DC

Residency
General Surgery, University of Tennessee Graduate School of Medicine

Fellowship
Vascular Surgery, University of Tennessee Graduate School of Medicine
Transplant Surgery, Washington Hospital Center, Washington, DC

Certifications

American Board of Surgery
American Board of Surgery/Vascular Surgery

Professional Affiliations

American College of Surgeons
Southeastern Surgical Congress
The Transplant Society
Association for Academic Surgery
American Society of Transplantation
The Society of Laparoscopic Surgeons
The Southern Association for Vascular Surgery
Tennessee Transplant Society
American Society of Transplant Surgeons
American College of Physician Executives
Society of Vascular Surgeons

Current Publications

Jagadish M, McNally MM, Heidel RE, Teffeteller S, Arnold JD, Freeman M, Stevens SL, Grandas OH, Goldman MH.
Diabetic foot ulcers: The importance of patient comorbidity recognition and total contact casting in successful wound care. The American Surgeon. 2016 Aug;82(8):733-736.

Freeman BM, Univers J, Fisher RK, Kirkpatrick SS, Klein FA, Freeman MB, Mountain DJH, Grandas OH.
Testosterone replacement attenuates intimal hyperplasia development in an androgen deficient model of vascular injury. Journal of Surgical Research. 2016 Aug 10. [Epub ahead of print]

Bools LM, Fisher RK, Grandas OH, Kirkpatrick SS, Arnold JD, Goldman MH, Freeman MB, Mountain DJH.
Comparative analysis of polymers for short interfering RNA delivery in vascular smooth muscle cells. The Journal of Surgical Research. 2015 Nov;199(1):266-73. Epub 2015 Jul 17.

Freeman BM, Mountain DJH, Brock TC, Chapman JR, Kirkpatrick SS, Freeman MB, Klein FA, Grandas OH.
Low testosterone elevates interleukin family cytokines in a rodent model: a possible mechanism for the potentiation of vascular disease in androgen-deficient males. Journal of Surgical Research. 2014 Jul;190(1):319-27.

Current Presentations

Univers J, Mountain D, Freeman B, Fisher R, Kirkpatrick S, Klein F, Freeman M, Grandas O. Urotensin's mechanistic role for development of intimal hyperplasia in androgen deficient males. Presented at Academic Surgical Congress; 2016 Feb 2-4; Jacksonville, FL.

Buckley MR, McNally MM, Arnold JD, Grandas OH, Stevens SL, Goldman MH, Carlson ER, Freeman MB. Clinical outcomes of double mandibular osteotomy for exposure of skull based carotid artery pathology. Presented at Southern Association for Vascular Surgery; 2016 Jan 20-23; Cancun, Mexico.

Buckley MR, Mountain DJ, Bools LM, Kirkpatrick SS, Whelan J, Terry P, Freeman MB, Grandas OH. Dietary Zyflamend inhibits intimal hyperplasia development via the attenuation of macrophage infiltration in a rodent model of vascular injury. Presented at Southern Association for Vascular Surgery; 2016 Jan 20-23; Cancun, Mexico.

Bools L, Buckley R, Mountain DJH, Kirkpatrick S, Whelan J, Terry P, Freeman MB, Grandas O. A poly-herbal dietary supplement, Zyflamend, inhibits matrix metalloproteinase expression and attenuates intimal hyperplasia in a rodent model of vascular disease. Presented at Society for Vascular Surgery; 2015 Jun 17-20; Chicago, IL.

Freeman BM, Mountain DJH, Brock TC, Chapman J, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Freeman MB, Klein FA, Grandas OH. Testosterone replacement attenuates hyperplasia development in an androgen deficient model of vascular injury independent of MMP regulation. Presented at Vascular Research Initiatives Conference and Arteriosclerosis, Thrombosis and Vascular Biology Peripheral Vascular Disease Scientific Sessions; 2015 May 6-9; San Francisco, CA.

Bools LM, Mountain DJ, Fisher RK, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Freeman MB, Grandas OH. Comparative analysis of polymers for siRNA delivery in vascular smooth muscle cells. Presented at 10th Annual Academic Surgical Congress; 2015 Feb 3-5; Las Vegas, NV.

Bools L, Buckley R, Mountain D, Kirkpatrick S, Whelan J, Terry P, Freeman M, Grandas O. Zyflamend: A poly-herbal extract, inhibits matrix metalloproteinases expression and attenuates intimal hyperplasia in a rodent model of vascular disease. Presented at Southern Association for Vascular Surgery; 2015 Jan 14-17; Scottsdale, AZ.

Bools LM, Mountain DJH, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Freeman MB, Grandas OH. Comparative analysis of polymers for siRNA delivery in vascular smooth muscle cells. Presented at Tennessee Chapter of American College of Surgeons; 2014 Aug 8-10; Buchanan, TN.

Freeman BM, Mountain DJH, Brock TC, Chapman JR, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Klein FA, Freeman MB, Grandas OH. Low testosterone elevates pro-inflammatory interleukin family cytokines: A possible mechanism for the potentiation of vascular disease in androgen deficient males. Presented at American Urological Assocation; 2014 May 16-21; Hollywood, FL.

Freeman BM, Mountain DJ, Brock TC, Chapman JR, Kirkpatrick SS, Arnold JD, Stevens SL, Goldman MH, Freeman MB, Klein FA, Grandas OH. Low testosterone elevates pro-inflammatory interleukin family cytokines: A possible mechanism for the potentiation of vascular disease in androgen deficient males. Presented at Academic Surgical Congress; 2014 Feb 4-6; San Diego, CA.

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