Publications
Foster J.S., Henley D.C., Seth P., and Wimalasena J. , Multifaceted Regulation of Cell Cycle Progression by Estrogens: Regulation of Cdk inhibitors and CDC 25A Independent of Cyclin D1-Cdk4 Function
Mol.Cell.Biol 21.794-810. 2001.
Ahamed S., Foster J.S., and Bukovsky A, Wimalasena J. , Signal Transduction via the Ras/Erk pathway is essential for Zearalenone induced cell cycle progression Mol Carcinogenesis 30, 88-98, 2001.
Foster JS, Henley DC, Ahammed A, Wimalasena J. Estrogens and Cell cycle regulation in Breast Cancer. Trends Endocrinol & Metab 12, 320-327, 2001.
Bukovsky A, Caudle MR, Keenan JA, Upadhyaya NB, Van Meter S, Wimalasena J , Elder RF. Association of mesenchymal cells and immunoglobulins with differentiating epithelial cells. BMC Dev. Biol 11, 2001.
Bukovsky A, Ayala ME, Dominguez R, Keenan JA, Wimalasena J , Caudle MR. Changes in ovarian interstitial cell hormone receptors and behavior of mesenchymal cells. Steroids 67, 277-289, 2002.
Bukovsky A, Cekanova M, Caudle MR, Wimalasena J , Foster JS, Keenan JA, Elder RF. Variability of Placental expression of Cyclin E, low molecular weight variants. Biol of Reproduction 67, 568-574 2002.
Ahmed S., Diehl J.A., Foster J.S., Wimalasena J. , Sequestration and down regulation of CKI are essential for activation of Cyclin E/Cdk2 in Zearalenone treated MCF7 breast cancer cells. Mol. Carcinogenesis .34.45-58,2002.
Placental expression of estrogen receptor beta and its hormone binding variant - comparison with estrogen receptor alpha and a role for estrogen receptors in asymmetric division and differentiation of estrogen-dependent cells. Bukovsky A, Caudle MR, Cekanova M, Fernando RI, Wimalasena J , Foster JS, Henley DC, Elder RF. Reprod Biol Endocrinol 2003 Apr 15;1(1):36.
Foster JS, Fernando RI, Ishida N, Nakayama KI, Wimalasena J. Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway. J Biol Chem. 2003 Oct 17;278(42):41355-66.
Bukovsky A, Cekanova M, Caudle MR, Wimalasena J , Foster JS,Henley DC,Elder RF Expression and localization of estogen receptor alpha protein in normal and abnormal term placentae and stimulation of trophoblast differentiation by estradio.l Rep Biol and Endocrinol 2003 1,13.
Fernando IR, Wimalasena J. Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and Akt. Mol Biol Cell. 2004 Jul;15(7):3266-84.
Ström A, Hartman J, Foster JS, Kietz S, Wimalasena J, Gustafsson JA. Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D. Proc Natl Acad Sci U S A. 2004 Feb 10;101(6):1566-71.
Hartman J, Müller P, Foster JS, Wimalasena J, Gustafsson JA, Ström A. HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1. Oncogene. 2004 Nov 18;23(54):8826-33.
Bukovsky A, Caudle MR, Svetlikova M, Wimalasena J, Ayala ME, Dominguez R. Oogenesis in adult mammals, including humans: a review. Endocrine. 2005 Apr;26(3):301-16.
Yamaguchi K, Lee SH, Kim JS, Wimalasena J, Kitajima S, Baek SJ. Activating transcription factor 3 and early growth response 1 are the novel targets of LY294002 in a phosphatidylinositol 3-kinase-independent pathway.
Cancer Res. 2006 Feb 15;66(4):2376-84.
Fernando R, Foster JS, Bible A, Ström A, Pestell RG, Rao M, Saxton A, Baek SJ, Yamaguchi K, Donnell R, Cekanova M, Wimalasena J. Breast cancer cell proliferation is inhibited by BAD: regulation of cyclin D1. J Biol Chem. 2007 Sep 28;282(39):28864-73.
Henley D, Isbill M, Fernando R, Foster JS, Wimalasena J.Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity. Cancer Chemother Pharmacol. 2007 Feb;59(2):235-49.
Liu T, Wimalasena J, Bowen RL, Atwood CS.
Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression.
J Neurochem. 2007 Mar;100(5):1329-39.
Noci I, Pillozzi S, Lastraioli E, Dabizzi S, Giachi M, Borrani E, Wimalasena J, Taddei GL, Scarselli G, Arcangeli A. hLH/hCG-receptor expression correlates with in vitro invasiveness in human primary endometrial cancer. Gynecol Oncol. 2008 Sep 30.
The University of Tennessee Graduate School of Medicine
1924 Alcoa Highway
Knoxville, TN
37920-6999
Phone: 865-305-8961