Cancer Cell Biology Laboratory
The Cancer Cell Biology Laboratory focuses on how growth and death of breast and ovarian cancer cells is regulated by estrogens and chemotherapy agents like paclitaxel. Specifically, researchers study the signal transduction pathways through which estrogens and paclitaxel regulate the cell cycle and apoptosis in cultured human breast and ovarian cancer cells. Our studies may in the future lead to identification of cellular targets in cancer cells which may prevent growth and or induce death in cancer cells.
Jay Wimalasena, PhD, Professor, Department of Obstretics and Gynecology and Director of the Cancer Cell Biology Laboratory, has been funded as a Principle Investigator by the US Department of Health & Human Services, National Institutes of Health for the last 22 years and is currently partially funded by a Department of Defense grant on Cancer Therapy and Imaging which was awarded to the UT Health Science Center in Memphis.
Dr. Wimalasena is the scientific editor for the journal Endocrine Related Cancers and is a also a reviewer in the breast/ovarian cancer field for several journals including Cancer Research, Clinical Cancer Research Molecular Cancer Research, Oncogene, Endocrine, Molecular Pharmacology and the European Journal of Cancer. Dr. Wimalasena also served as a scientific review panel member for the Department of Defense - Breast Cancer Research Program from 200-2007.
The University of Tennessee Graduate School of Medicine
1924 Alcoa Highway
Knoxville, TN
37920-6999
Phone: 865-305-9290
or 800-596-7249