The University of Tennessee Graduate School of Medicine, Knoxville



The Department of Radiology

Alexander Pasciak, PhD

Clinical Associate Professor

Research Focus

Medical Physics

Education

Graduate School

PhD, Nuclear Engineering with emphasis in Radiation Biology, Texas A&M University, College Station, TX 2007
MS, Health Physics, Texas A&M University, College Station, TX, 2005

Post Graduate School
Diagnostic Medical Physics Residency, Department of Imaging Physics, The University of Texas, MD Anderson Cancer Center, Houston, TX, 2008-2010
Research Fellowship, Pacific Northwest National Laboratory, Hanford, WA. 2003-2004

Certifications

Diplomate of the American Board of Radiology, Diagnostic Medical Physics
Mammography Quality Standards Act (MQSA) Qualified Medical Physicist
State of Tennessee Certified Inspector of Class 1, 3 and 5 X-ray equipment

Honors and Awards

Excellence in Teaching Award, presented by The University of Tennessee Graduate School in Medicine, 2013
Received best presentation award for submission of the abstract, A.S. Pasciak and A. K. Jones; Clinical Measurement of Anti-Scatter Grid Ratio in Conventional Radiography; Spr. 2009 Southwest American Association of Physical Medicine, 2009

Professional Affiliations

American Association of Physics in Medicine, Full Member
Southeast Chapter of the AAPM
American College of Radiology

Current Publications

Pasciak AS, Bourgeois AC, Paxton BE, Nodit L, Coan PN, Kraitchman D, Stinnett SS, Patel VM, Fu Y, Adams JK, Tolbert MK, Lux CN, Arepally A, Bradley YC.
Bariatric radioembolization: A pilot study on technical feasibility and safety in a porcine model. Journal of Vascular and Interventional Radiology. 2016 Aug 1. [Epub ahead of print]

Pasciak AS, Nodit L, Bourgeois AC, Paxton BE, Coan PN, Clark CT, Tolbert MK, Adams JK, Arepally A, Bradley YC.
How sensitive is the upper gastrointestinal tract to Yttrium 90 radioembolization? A histologic and dosimetric analysis in a porcine model. Journal of Nuclear Medicine. 2016 Jul 7. [Epub ahead of print]

Jones AK, Pasciak AS, Wagner LK.
Sensitivity of the diagnostic radiological index of protection to procedural factors in fluoroscopy. Medical Physics. 2016 Jul;43(7):4133.

Pasciak AS, Bourgeois AC.
Comments on: Intrahepatic activity distribution in radioembolization with yttrium-90-labeled resin microspheres using the body surface area method-A less than perfect model. Journal of Vascular and Interventional Radiology. 2016 Feb;27(2):297-8.

Kyle Jones A, Pasciak AS.
Comments on "Evaluation of a noise reduction imaging technology in iliac digital subtraction angiography: Noninferior clinical image quality with lower patient and scatter dose". Journal of Vascular and Interventional Radiology. 2015 Sep;26(9):1419-20.

Willowson KP, Tapner M, QUEST Investigator Team (Bourgeois AC, Bradley YC, Pasciak AS, et al.), Bailey DL.
A multicentre comparison of quantitative (90)Y PET/CT for dosimetric purposes after radioembolization with resin microspheres: The QUEST Phantom Study. European Journal of Nuclear Medicine and Molecular Imaging. 2015 Jul;42(8):1202-22. Epub 2015 May 13.

Pasciak A, Jones A, Wagner L.
TH-AB-201-05: Sensitivity of the diagnostic radiological index of protection (DRIP) to the scatter spectrum in fluoroscopy. Medical Physics. 2015 Jun;42(6):3718.

Bourgeois AC, Kolze CT, Guimaraes MS, Pasciak AS, Ferrell AS, Bradley Y, Kvamme P.
Safety and efficacy of combined micropuncture and shallow angle femoral artery access for neurovascular angiography. The Journal of Vascular Access. 2015 May 23. [Epub ahead of print]

Pasciak AS, McElmurray JH, Bourgeois AC, Heidel RE, Bradley YC.
The impact of an Antireflux catheter on target volume particulate distribution in liver-directed embolotherapy: A pilot study. Journal of Vascular and Interventional Radiology. 2015 May;26(5):660-9. Epub 2015 Mar 20.

Faulkner AR, Bourgeois AC, Bradley YC, Hudson KB, Heidel RE, Pasciak AS.
Simulation-based educational curriculum for fluoroscopically guided lumbar puncture improves operator confidence and reduces patient dose. Academic Radiology. 2015 May;22(5):668-673.

Bourgeois AC, Faulkner AR, Pasciak AS, Bradley YC.
The evolution of image-guided lumbosacral spine surgery. Annals of Translational Medicine . 2015 Apr;3(5):69.

Pasciak AS, Kyle Jones A, Wagner LK.
Application of the diagnostic radiological index of protection to protective garments. Medical Physics . 2015 Feb;42(2):653-62.

Faulkner AR, Bourgeois AC, Bradley YC, Pasciak AS.
A robust and inexpensive phantom for fluoroscopically guided lumbar puncture training. Simulation in Healthcare : Journal of the Society for Simulation in Healthcare . 2015 Feb;10(1):54-8.

Bourgeois AC, Bradley YC, McElmurray J, Pasciak A.
Does the number of infused microspheres impact tumor dose in radioembolization? An analysis of resin versus glass Yttrium-90 microspheres. Journal of Vascular and Interventional Radiology . 2015 Feb;26(2):S111.

Pasciak AS, Bourgeois AC, Jones AK.
C-arm rotation as a method for reducing peak skin dose in interventional cardiology. Open Heart . 2014 Dec 23;1(1):e000141.

Pasciak AS, Kyle Jones A.
Time to take the gloves off: The use of radiation reduction gloves can greatly increase patient dose. Journal of Applied Clinical Medical Physics . 2014;15(6):351-359.

Bourgeois AC, Faulkner AR, Bradley YC, Pasciak A, Barlow PB, Gash JR, Reid Jr WS.
Improved accuracy of minimally invasive transpedicular screw placement in the lumbar spine with three-dimensional stereotactic image guidance: A comparative meta-analysis. Journal of Spinal Disorders and Techniques. 2014 Aug 1. [Epub ahead of print]

Jones AK, Ensor JE, Pasciak AS.
How accurately can the peak skin dose in fluoroscopy be determined using indirect dose metrics? Medical Physics. 2014 Jul;41(7):071913.

Pasciak AS, Bourgeois AC, Bradley YC.
A comparison of techniques for (90)Y PET/CT image-based dosimetry following radioembolization with resin microspheres. Frontiers in Oncology . 2014 May 22;4:121.

Bourgeois AC, Chang TT, Bradley YC, Acuff SN, Pasciak AS.
Intraprocedural yttrium-90 positron emission tomography/CT for treatment optimization of yttrium-90 radioembolization. Journal of Vascular and Interventional Radiology : Jvir . 2014 Feb;25(2):271-5.

Pasciak AS, Bourgeois AC, McKinney JM, Chang TT, Osborne DR, Acuff SN, Bradley YC.
Radioembolization and the dynamic role of Y PET/CT. Frontiers in Oncology . 2014 Feb 27;4:38. eCollection 2014.

Current Presentations

Patel V, Pasciak AS, Bourgeois AC, Bradley YC, Nodit L. Histopathologic sequela of bariatric radioembolization for Ghrelin reduction and weight loss in a porcine model. Presented at College of American Pathologists, CAP16 The Pathologists' Meeting; 2016 Sep 25-28; Las Vegas, NV.

Pasciak A, Bradley Y, Nodit L, Bourgeois A, Paxton B, Arepally A. Radiation therapy as a potential treatment for obesity: Initial data from a preclinical investigation. Presented at American Association of Physics in Medicine; 2016 Jul 31 - Aug 4; Washington, DC.

Pasciak A, Bradley Y, Nodit L, Bourgeois A, Paxton B, Arepally A. Radiation therapy as a potential treatment for obesity: Initial data from a preclinical investigation. Presented at American Association of Physics in Medicine; 2016 Jul 31 - Aug 4; Washington, DC.

Pasciak A, Nodit L, Bourgeois A, Paxton B, Arepally A, Bradley Y. A dosimetric investigation into the effects of Yttrium-90 radioembolization on the GI tract: In-vivo and histological analysis in an animal model. Presented at American Association of Physics in Medicine; 2016 Jul 31 - Aug 4; Washington, DC.

Pasciak A, Nodit L, Bourgeois A, Paxton B, Arepally A, Bradley Y. A dosimetric investigation into the effects of Yttrium-90 radioembolization on the GI tract: In-vivo and histological analysis in an animal model. Presented at American Association of Physics in Medicine; 2016 Jul 31 - Aug 4; Washington, DC.

Pasciak AS, Bourgeois AC, Arepally A, Paxton B, Coan PN, Nodit L, Adams JK, Patel VJ, Bradley YC. Bariatric Radiation Therapy (BaRT): Proof of concept in porcine model. Presented at Society of Interventional Radiology Annual Meeting; 2016 Apr 2-7; Vancouver, Canada.

Bourgeois AC, Pasciak AS, Bradley YC, Arepally A, Paxton B, Coan PN, Adams JK, Nodit L. How sensitive is the upper GI tract to 90Y radioembolization? Gross pathological analysis as a function of absorbed dose in a porcine model. Presented at Society of Interventional Radiology Annual Meeting; 2016 Apr 2-7; Vancouver, Canada.

Bourgeois AC, Bradley YC, McElmurray J, Robinson CA, Heidel ER, Pasciak AS. The effect of anti-reflux catheters on pulmonary shunt fraction in patients with hepatocellular carcinoma. Presented at World Conference Interventional Radiology; 2015 May 6-9; New York, NY.

Syed M, Bradley YC, Pasciak AS, Bourgeois AC. A review of operative complications following lumbar spine surgery. Presented at American Society of Spine Radiology; 2015 Feb 5-8; Las Vegas, NV.

Bourgeois AC, Bradley YC, McElmurray J, Pasciak A. Does the number of infused microspheres impact tumor dose in radioembolization? An analysis of resin versus glass yttrium-90 microspheres. Presented at Society of Interventional Radiology; 2015 Feb 28 - Mar 5; Atlanta, GA.

Bourgeois AC, Pasciak A, Bradley YC, Heidel RE, McElmurray J. The impact of an anti-reflux catheter on downstream particulate distribution in liver directed embolotherapy: An in-vivo analysis. Presented at Society of Interventional Radiology; 2015 Feb 28 - Mar 5; Atlanta, GA.

Frederick-Dyer K, Faulkner A, Hudson KT, Pasciak AS. E-learning physics: A resource guide for radiology residents. Presented at Radiological Society of North America; 2014 Nov 30 - Dec 5; Chicago, IL.

Bourgeois A, Bradley Y, Pasciak A. The local deposition method: A simplified mechanism of direct yttrium-90 dosimetry utilizing PET/CT with comparable accuracy to dose-point kernel convolution. Presented at Radiological Society of North America; 2014 Nov 30 - Dec 5; Chicago, IL.

Faulkner A, Bourgeois A, Stanborough R, Pasciak AS, Bradley YC. Multimodality imaging of mandibular lesions: A jaw-dropping differential. Presented at American Society of Head & Neck Radiology; 2014 Sep 10-14; Seattle, WA.

Pasciak A, Jones A, Wagner L. Matching primary and scattered X-ray spectra for use in calculating the diagnostic radiation index of protection. Presented at Association of Physicists in Medicine Annual Meeting; 2014 Jul 20-24; Austin, TX.

Pasciak A, Bradley Y, Bourgeois A. Applications of quantitative PET/CT imaging of Yttrium-90: A tool for improving radioembolization. Presented at Association of Physicists in Medicine Annual Meeting; 2014 Jul 20-24; Austin, TX.

Pasciak A, McElmurray J, Bourgeois A, Bradley Y. A medical physics approach to the evaluation of a new anti-reflux catheter. Presented at Association of Physicists in Medicine Annual Meeting; 2014 Jul 20-24; Austin, TX.

Pasciak A, Kao J, Bourgeois A, Bradley Y. Y90 PET/CT for the instantaneous determination of both target and non-target absorbed doses following hepatic radioembolization. Presented at Association of Physicists in Medicine Annual Meeting; 2014 Jul 20-24; Austin, TX.

Jones A, Pasciak A. How accurately can the peak skin dose in fluoroscopy be determined using indirect dose metrics? Presented at Association of Physicists in Medicine Annual Meeting; 2014 Jul 20-24; Austin, TX.

Pasciak A, Bourgeois A. Balancing image quality and dose in radiography. Presented at Association of Physicists in Medicine Annual Meeting; 2014 Jul 20-24; Austin, TX.

Faulkner AR, Bourgeois AC, McElmurray JH, Bradley YC, Findeiss LK, Pasciak AS. The effect of the surefire antireflux catheter on downstream particulate distribution: Preliminary results from 4 patients. Presented at Global Embolization Symposium and Technologies; 2014 May 1-4; San Francisco, CA.

McLaren TA, Bourgeois AC, Faulkner AR, Hudson KB, Pasciak AS. Creating an inexpensive educational lumbar spine model for teaching fluoroscopy-guided intervention. Presented at Association of University Radiologists 62nd Annual Meeting; 2014 Apr 1-4; Baltimore, MD.

Kao JL, Bourgeois AC, Chang TT, Findeiss LK, McElmurray JH, Bradley YC, Pasciak AS. How to determine absorbed dose following radioembolization using Y90 PET/CT: A clinician's guide. Presented at Society of Interventional Radiology; 2014 Mar 22-27; San Diego, CA.

Bourgeois AC, McLaren T, Hudson K, Pasciak AS, Faulkner AR, Heidel E, Bradley YC. Simulation-based educational curriculum for lumbar puncture to improve operator confidence and efficiency. Presented at American Society of Spine Radiology; 2014 Feb 13-16; Miami Beach, FL.

Bourgeois A, Luttrell L, McElmurray J, Findeiss L, Biddle D, Badley Y, Pasciak A. Current and future applications of yttrium-90 PET/CT imaging following radioembolization: A case-based approach. Presented at International Symposium on Clinical Interventional Oncology; 2014 Jan 18-19; Miami Beach, FL.

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