Karl F. Hubner, MD
Professsor Emeritus, Department of Radiology
Education
M.D. Univ. of Heidelberg Medical School, Germany, 1959
Department of Radiology
University of Tennessee Medical Center
1924 Alcoa Highway
Knoxville, TN 37920
Phone: (865) 305-9662
Fax: (865) 305-8883
Research Interests
Oncology in PET and Nuclear Medicine
Publications
Nahmias C, Carlson ER, Duncan LD, Blodgett TM, Kennedy J, Long MJ, Carr C, Hubner KF, Townsend DW.
Positron emission tomography/computerized tomography (PET/CT) scanning for preoperative staging of patients with oral/head and neck cancer.
J Oral Maxillofac Surg. 2007 Dec;65(12):2524-35.
PMID: 18022480
Thie JA, Hubner KF, Isidoro FP, Smith GT.
A weight index for the standardized uptake value in 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography.
Mol Imaging Biol. 2007 Mar-Apr;9(2):91-8.
PMID: 17205367
Nahmias C, Hanna WT, Wahl LM, Long MJ, Hubner KF, Townsend DW.
Time course of early response to chemotherapy in non-small cell lung cancer patients with 18F-FDG PET/CT.
J Nucl Med. 2007 May;48(5):744-51.
PMID: 17475962
Delbeke D, Coleman RE, Guiberteau MJ, Brown ML, Royal HD, Siegel BA, Townsend DW, Berland LL, Parker JA, Hubner K, Stabin MG, Zubal G, Kachelriess M, Cronin V, Holbrook S. Procedure guideline for tumor imaging with 18F-FDG PET/CT 1.0.
J Nucl Med. 2006 May;47(5):885-95.
Erratum in: J Nucl Med. 2006 Jun;47(6):903.
PMID: 16644760
Thie JA, Smith GT, Hubner KF.
2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography sensitivity to serum glucose: a survey and diagnostic applications.
Mol Imaging Biol. 2005 Sep-Oct;7(5):361-8.
PMID: 16228119
Smith GT, Isidoro F, Thie JA, Hubner KF.
Optimal diagnosis by using two-marker studies.
Radiology. 2003 Jul;228(1):292-3; author reply 293.
PMID: 12832591
Thie JA, Hubner KF, Smith GT.
Optimizing imaging time for improved performance in oncology PET studies.
Mol Imaging Biol. 2002 May;4(3):238-44.
PMID: 14537128
Thie JA, Hubner KF, Smith GT.
The diagnostic utility of the lognormal behavior of PET standardized uptake values in tumors.
J Nucl Med. 2000 Oct;41(10):1664-72.
PMID: 11037996 [PubMed
Hubner KF, Thie JA, Smith GT, Chan AC, Fernandez PS, McCoy JM.
Clinical Utility of FDG-PET in Detecting Head and Neck Tumors. A Comparison of Diagnostic Methods and Modalities.
Clin Positron Imaging. 2000 Jan;3(1):7-16.
PMID: 10742677
Hubner KF, McDonald TW, Smith GT, Thie JA.
Detection of Recurrent Ovarian Cancer by PET Using FDG.
Clin Positron Imaging. 1999 Nov;2(6):346. No abstract available.
PMID: 14516643
Vomocil B, Hanna W, Bell J, Hunter KM, Hubner KF. The Impact of F-18-FDG PET on the Management and Survival of Patients with Primary and Suspected Recurrent Colorectal Cancer.
Clin Positron Imaging. 1999 Nov;2(6):347.
PMID: 14516644
Thie JA, Hubner KF, Smith GT.
Model Interpretation and Clinical Implications.
Clin Positron Imaging. 1999 Mar;2(2):99-104.
PMID: 14516546
Smith GT, Hubner KF, McDonald T, Thie JA.
Cost Analysis of FDG PET for Managing Patients with Ovarian Cancer.
Clin Positron Imaging. 1999 Mar;2(2):63-70.
PMID: 14516542
Hubner KF, Thie JA, Smith GT, Kabalka GW, Keller IB, Kliefoth AB, Campbell SK, Buonocore E.
Positron Emission Tomography (PET) with 1-Aminocyclobutane-1-[(11)C]carboxylic Acid (1-[(11)C]-ACBC) for Detecting Recurrent Brain Tumors.
Clin Positron Imaging. 1998 Jun;1(3):165-173.
PMID: 14516591
Hubner KF, Thie JA, Hunter K, Smith GT.
Pitfalls in PET Oncology when Interpreting Whole Body PET Images Corrected for Attenuation.
Clin Positron Imaging. 1998 Sep;1(4):264. No abstract available.
PMID: 14516587
Smith GT, Hubner KF, McDonald T, Thie JA.
Avoiding Second-Look Surgery and Reducing Costs in Managing Patients with Ovarian Cancer by Applying F-18-FDG PET.
Clin Positron Imaging. 1998 Sep;1(4):263.
PMID: 14516586
Laningham FH, Smith GT, Hanna WT, Hubner KF.
The Impact of Whole Body FDG PET on the Management of Patients with Malignant Melanoma.
Clin Positron Imaging. 1998 Sep;1(4):262.
PMID: 14516585
Smith GT, Hubner KF, Legendre AM, Matwichuk CL, Daniel GB.
FDG Accumulation in Disseminated Blastomyces Dermatitidis in a Dog.
Clin Positron Imaging. 1998 Sep;1(4):261.
PMID: 14516584
Smith GT, Hubner KF, Peterson A, Hunter K, Neff J.
FDG PET for Evaluation of Bronchioloalveolar Cell Carcinoma (BAC) of the Lung.
Clin Positron Imaging. 1998 Sep;1(4):260.
PMID: 14516583
Thie JA, Smith GT and Hubner KF. Linear Least Squares Compartmental Model Independent Parameter Identification in PET. IEEE Transactions in Medical Imaging 16:1116 (1997).
Hubner KF, Buonocore E, Gould HR, et al. Differentiation of Benign from Malignant Lung Lesions Based on Parameters of PET Images Obtained with 2[18F]FDG. Diagnostic Oncology 4(5):261 (1996).
Singh RP, Smith GT and Hubner KF. In111 Octreotide Uptake in Substernal Colloid Goiter. Clinical Nuclear Medicine 21:643662 (1996).
Hubner KF, Buonocore E, Gould HR, Thie J, Smith GT, Stephens S and Dickey J. Differentiation of Benign from Malignant Lung Lesions Based on Parameters of PET Images Obtained with 2[18F]FDG. Diagnostic Oncology 4(5):261 (1996).
Hubner KF, Buonocore E, Gould HR, Thie J, Smith GT, Stephens, S and Dickey J. Differentiating Benign from Malignant Lung Lesions Using "Quantitative" Parameters of FDG PET Images. Clinical Nuclear Medicine 21:941949 (1996).
SariSarraf H, Gleason SS, Redmon CG, Hudson KT and Hubner KF. Higher Accuracy and Throughput in ComputerAided Screening of Mammographic Microcalcifications.( Radiology, in press.)
SariSarraf H, Gleason SS, Hudson KT and Hubner KF. A Novel Approach to Computer Aided Diagnosis of Mammographic Images. Accepted for publication in IEEE Transactions on Medical Imaging.
Hubner KF, Thie J, Smith GT and Bond H. Mechanism of Uptake of 1[C11]aminocyclobutanecarboxylic acid (1[C11]ACBC) by Brain Tumours Examined by a New Multiple Time Graphical Analysis of Image Data Acquired by Positron Emission Tomography. In: Proceedings of the 19th L H Gray Conference: Quantitative Imaging in Oncology, Faulkner K, Carey B, Crellin A and Harrison RM, eds. Published by the British Institute of Radiology, London, England, 1996, pp. 2022.
E-mail: khubner@utmck.edu