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Conference Takes to the Streets
What is the impact of street drugs? On April 22, 2005, the Office of Continuing Medical Education (CME) hosted a cutting-edge conference that answered that question by examining the forensics of drug toxicity and the impact of abuse of prescriptions, over-the-counter and "street" drugs.
The one-day event, "Street Wise: Pharmacology, Forensics and Abuse of Street Drugz and 'Scrips," attracted over 140 dentists, oral surgeons, dental office personnel, nurses, public health officials, pharmacists and physicians. The conference was led by UT College of Pharmacy's Glen Farr, PharmD, and Department of Pathology faculty member Darinka Mileusnic, MD, PhD.
Fees for the conference were subsidized by the John E. Sullivan DDS Memorial Endowed Lecture and the conference was co-sponsored by GSM, Department of Oral and Maxillofacial Surgery and the UT College of Pharmacy.
Signs of Abuse Conference Answers Questions
Would you recognize the signs of drug abuse?CME hosted a half day course entitled, "Substances of Abuse: An Overview," on Friday, May 20, 2005. More than 100 attendees listened as H. Thomas Milhorn, MD, PhD, of the University of Mississippi School of Medicine led participants in an overview of drugs of choice and detection of drug abuse.
The conference fee was subsidized by the Patterson Domestic Violence and Child Abuse Education Gift Fund. Sponsors included GSM, Department of Family Medicine and the Patterson fund.
Workshop Explains Grand Rounds Requirements
Understanding the requirements for planning and certifying Grand Rounds and other Series activities is complicated. A free workshop, held May 23 and 24, through the office of CME, helped explain those requirements to Grand Rounds and Series coordinators. Coordinators should call CME at 305-9190 or email if they have questions about the materials supplied at the workshop.
CME Upcoming Events:
21st Annual Alzheimer's Disease Symposium
June 6-7, 2005, Park Vista Hotel, Gatlinburg
PALS (Pediatric Advanced Life Support)
June 14-15, 2005, UT Conference Center, Knoxville
ACLS (Advanced Cardiac Life Support)
June 21-22, 2005, UT Conference Center, Knoxville
CyberKnife Radiosurgery
June 22, 2005, Riverside Tavern, Knoxville
8th Annual Psychiatric Symposium
August 25-26, Convention Center, Knoxville
Pathology Residents' Research Day is Success

Pathology Residents Research Day was held on June 1, 2005. Presentations included:
Demodex folliculitis: A case report and review of the literature by Huijun Dong, MD, PhD, current Cytopathology Fellow.
Atypical squamous cells, cannot exclude a high grade lesion: The practice experience of a hospital-based reference laboratory with the new Bethesda System Diagnostic Category by Sanjivini V. Jacob, MD, third year resident.
Impact of the 2003 American Joint Committee on Cancer Staging for melanoma by James J. Lyons, MD, second year resident.
Progressive fatal encephalopathy in an immunosuppressed patient with a history of discoid lupus erythematosus by Vedran Uschuplich, MD, third year resident.
General Dentistry Welcomes New Residents:
- Jeremy Bayer, DDS, University of Michigan, Ann Arbor, MI
- Elizabeth Brinker, DDS, Virginia Commonwealth Dental School, Richmond, VA
- David Celello, DDS, Temple University, Pittsburgh, PA
- Tatum (T.J.) Fowler, DDS, UT Memphis School of Dentistry, Memphis, TN
- Benjamin (Ben) Scott, DDS, UT Memphis School of Dentistry, Memphis, TN
Department of Family Medicine Welcomes Sixth Class of Emergency Medicine Fellows:
- Kevin Catney, MD, St. Joseph Hospital Family Practice Residency Program, Houston, TX
- Nathan Gilbert, DO, UT Family Medicine Residency Program, Knoxville, TN
- Roshan Mathews, MD, Seneca Lakes Rural Family Medicine Program, Seneca, SC
- Abdolreza Rabiee, MD, St. Elizabeth Family Practice Residency Program, Edgewood, KY
UTRA Plans Annual Picnic
The University of Tennessee Residents Alliance (UTRA) would like to invite all residents and their families to the annual "Welcome Family Picnic at The Cove” on July 24 at noon . UTRA is the spouses network for the UT Graduate School of Medicine's Residency
Programs. Please contact UTRA for more information.
Ob/Gyn Faculty Attend ACOG 2005 Clinical Meeting
Robert F. Elder, MD and Nikki B. Zite, MD, faculty in the Department of Obstetrics and Gynecology, recently attended and presented at the 53rd Annual Clinical Meeting of the American College of Obstetricians and Gynecologists (ACOG) in San Francisco, CA. Dr. Elder's topic of discussion was entitled, "Interstitial Cystitis - Stop the Pain." Dr. Zite presentations included: "Postpartum Tubals, Does Anyone Do Them Anymore?" and "Emergency Contraception: Make Your Patients Aware - Before the Emergency."
Dr. Zite also had two poster presentations:
- "Public Aid Sterilization Papers: Attitudes and Misconceptions"
- "Reasons Women Fail to Obtain Desired Postpartum Sterilization"
Anesthesiology Department Poster Presentations:
Society of Obstetrical Anesthesiology and Perinatology, 37th Annual Meeting, May 2005, Palm Desert, CA:
"The Consequences of High Risk Behaviors: A Review of Trauma in Pregnancy" by
Patteson SK, Whitaker GL, Snider CC, Meyer DS, Enderson BL, Armstrong JE, Carroll RC
Society of Cardiovascular Anesthesiology, 27th Annual Meeting & Workshops, May 2005, Baltimore, MD:
"Modified Thrombelastography for Measuring Platelet Reactivity preoperatively in Cardiopulmonary Bypass Patients."by
Chavez JJ, Simmons JW, Snider CC, Meyer DS, Carroll, RC
17th Annual Symposium of the American Academy of Medical Acupuncture:
"A Trial of Acupuncture for Chronic Pelvic Pain and Interstitial Cystitis" by
Bagley WP
Medicine Faculty attend AHME 2005 Spring Educational Institute
Kimberly Morris, MD, and Daphne Norwood, MD, were invited presenters at the Association for Hospital Medical Education (AHME) Spring Educational Institute recently held in Tucson, AZ. Dr. Norwood's poster presentation was entitled, "Getting to the Point: Evaluation of a Four Point Grading Scale Compared to the Nine Point ABIM Grading Scale in an Internal Medicine Residency Program." Dr. Norwood received statistical assistance from Dr. David Hollar, PhD, Department of Medical Genetics.
Dr. Morris poster presentation was "The Role of Key Faculty Coordinating Core Competency Based Specialty Training in Internal Medicine."
Postdoctoral Student Presents Poster at ACS
Arjun R. Mereddy, PhD, postdoctoral student in the laboratory of Dr. George Kabalka, Department of Radiology, presented a poster at the 229th American Chemical Society (ACS)National Meeting and Exposition recently in San Diego, CA. His poster topic was "Synthesis of Iodine-123 Labeled COX-2 Inhibitor: A Potential SPECT Agent." Co-presenters included George W. Kabalka, PhD and Hildegard Schuller, MD, PhD.
Two articles were recently published:
Kabalka GW, Mereddy AR, Schuller HM
Synthesis of an iodine-123-labeled celecoxib analogue: a potential SPECT agent.
Journal of Labelled Compounds & Radiopharmaceuticals 2005; 48: 295-300.
Kabalka GW, Mereddy AR
A facile synthesis of radioiodinated alkynyl iodides using potassium alkynyltrifluoroborates.
Journal of Labelled Compounds & Radiopharmaceuticals 2005; 48: 359-362.

Medical Library Offers 2005 DVD Edition of "MedStudy" Board Review of Internal Medicine
Internal Medicine Residents can now study for their Boards using a new 20 DVD set which includes over 60 hours of presentations from the 2004 MedStudy Intensive Board Review as well as a syllabus containing text, diagrams and slides from each speaker. The DVD's may be checked out for a two week period.
Popular Resource Renewed for 2005-2006
Preston Medical Library will renew UpToDate for the next fiscal year. This resources has an average of more than 150 uses per day from our institution. UpToDate is specifically designed to answer clinical questions that arise in daily practice right at the point of care. The published evidence is summarized and specific recommendations can be made for patient care. Questions? Email or call the library at 305-9525.

The following list of publications reflects only journal articles indexed in PubMed (MEDLINE). If you are interested in obtaining a copy of an article listed, please contact Preston Medical Library.
Kendrick JM, Wilson C, Elder RF, Smith CS.
Reliability of reporting of self-monitoring of blood glucose in pregnant women.
J Obstet Gynecol Neonatal Nurs. 2005 May-Jun;34(3):329-34.
PMID: 15890831
Kabalka GW, Yao ML, Borella S, Wu Z.
Alkenylation of allylic alcohols using alkenylboron dihalides: a formal transition-metal free Suzuki reaction.
Chem Commun (Camb). 2005 Jun 7;(19):2492-4. Epub 2005 Mar 31.
PMID: 15886781
Williams AD, Sega M, Chen M, Kheterpal I, Geva M, Berthelier V, Kaleta DT, Cook KD, Wetzel R.
Structural properties of A{beta} protofibrils stabilized by a small molecule.
Proc Natl Acad Sci U S A. 2005 May 17;102(20):7115-20. Epub 2005 May 9.
PMID: 15883377
Goldman MH.
Masters and commanders.
J Vasc Surg. 2005 Apr;41(4):725-8. No abstract available.
PMID: 15874942
Bukovsky A, Svetlikova M, Caudle MR.
Oogenesis in cultures derived from adult human ovaries.
Reprod Biol Endocrinol. 2005 May 5;3(1):17.
PMID: 15871747
Carroll RC, Owers RL, Elder RF, Hennessey MD, Patteson SK, Snider CC, Muenchen RA.
Lack of thrombopoietin potentiation of platelet collagen activation in the first trimester is associated with preeclampsia.
Thromb Res. 2005;116(1):51-4. Epub 2004 Dec 2.
PMID: 15850608
Xenos ES, Stevens SL, Freeman MB, Cassada DC, Goldman MH.
Nitric oxide mediates the effect of fluvastatin on intercellular adhesion molecule-1 and platelet endothelial cell adhesion molecule-1 expression on human endothelial cells.
Ann Vasc Surg. 2005 May;19(3):386-92.
PMID: 15818460
Craft RM, Chavez JJ, Snider CC, Muenchen RA, Carroll RC.
Comparison of a modified Thrombelastograph and PlateletWorks whole blood assay to optical platelet aggregation for monitoring reversal of clopidogrel inhibition in elective surgery patients.
J Lab Clin Med (in press, 2005)
Carroll RC, Craft RM, Chavez JJ, Snider CC, Bresee SJ, Cohen E.
A thrombelastograph whole blood assay for clinical monitoring of NSAID-insensitive transcellular platelet-activation by arachidonic acid.
J Lab Clin Med (in press, 2005)

Updating your PDA (Cynthia Vaughn, leader)
June 21 12:00 – 1:00 Library Training Room
Are you ... ready to take your PDA to the next level?
Learn to ... install medical software such as calculators and drug databases and how to use them.
Let's Meet! (Missy Maples, leader)
Date to be Announced
Do you ... want to schedule a meeting but don't want to get bogged down calling all the attendees? have access to Outlook?
Learn to ... schedule a meeting in Outlook and have the confirmation of attendance come directly to your inbox.
To Sign up for any class, contact:
Genny Kirchner in the Dean's Office at ext. 8371 or gkirchne@utmck.edu
Register early as class space is limited!
If you have news or an event to announce via this newsletter and/or the GSM Web site, please submit your story.

Editor
Connie Littleton
Editorial Staff
Alison Lockett, Sherry Brewer,
and James Neutens, PhD
©2005 The University of Tennessee
Graduate School of Medicine
Newsletter Feedback

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Moore Completes GME Leadership Course
Eddie S. Moore, MD, Designated Institutional Official, Graduate Medical Education (GME), successfully completed the Association of American Medical Colleges' (AAMC) "GME Leadership Development Course." Dr. Moore was among 45 graduates from institutions across the country to earn this certificate in April 2005. The 43.5-hour course, organized by the AAMC Group on Resident Affairs, is designed to help participants fulfill their responsibilities as graduate medical leaders and designated institutional officials (DIO's). The course is exclusively offered to academic leaders who manage the institutional environment for residents and fellows. It explores all aspects of the DIO's responsibilities including: leading an institution through accreditation; meeting the Accreditation Council for Graduate Medical Education's new resident duty hours requirements; and educational program improvement.
GSM Research Associate Appointed
In an effort to assistant faculty, residents and staff in pursuing research, the Graduate School of Medicine (GSM) has announced the appointment of Cynthia L. Langley, RN, to the newly-created position of GSM Research Associate. In her position, Ms. Langley will offer consultation and advice on research design as well as review protocols and informed consent documents.
Faculty, residents or staff who are initiating new studies, including chart review, survey research or IRB applications, may contact Ms. Langley at 305-6892 or via email.

Article Generates International Interest
A recent article published by Drs. Antonin Bukovsky, Marta Svetlikova and Michael R. Caudle has received international interest because of a breakthrough discovery. The article entitled, "Oogenesis in cultures derived from adult human ovaries," was published in the peer reviewed journal, Reproductive Biology and Endocrinology. This articles follows an article written ten years ago when Dr. Bukovsky and colleagues reported that in females the ovarian surface epithelium is a source of germ stem cells. Now they have been able to use ovarian stem cells to grow human eggs in vitro.
Dr. Bukovsky explains that this discovery could lead to new fertility treatments and enable women to delay menopause for decades. "Now women will not have to accept the limited quota of eggs they are born with and can be capable of producing new eggs later in life," says Dr. Bukovsky.
He is Professor and Director of the Laboratory of
Development, Differentiation and Cancer in the Department of Obstetrics and Gynecology and Editor-in-Chief of Reproductive Biology and Endocrinology.
International, national and local newspaper and television reports have covered the story with continued interest. BioMed Central, the open access Internet-based publisher, lists this article as one of the most viewed articles in the last 30 days. The Preston Medical Library has an institutional membership to BioMed Central which allows GSM faculty to publish in BioMed Central journals without paying any additional article processing charges.
Smith Participates in Television Adventure Competition - The Nevada Passage
Audie Smith, MD, Assistant Professor, Department of Anesthesiology, really enjoys mountain biking, swimming, and running.
His enthusiasm for sports and his participation in adventure races sponsored by Xterra has led him to television! He was asked to be part of a new television adventure competition called "The Nevada Passage." The Nevada Passage was held May 19-24, 2005. The competitors were matched (groups of two) according their occupations. Dr. Smith was paired with Kathleen Coutinho, a chiropractor from Virginia who had just given birth six months ago.

The athletes took part in rock climbing, a jet ski time trial, a 4WD treasure hunt, mountain biking, sand board time trials, and white water kayaking in their six-day adventure across Nevada. A one-hour feature television show will be produced for syndication in the U.S. beginning August 2005.
Matteson Appointed to International Steering Committee
Karla J. Matteson, PhD, Associate Professor, Department of Medical Genetics, was chosen to be the US Representative of the Steering Committee for "Guidelines for Best Practices in Quality Assurance for Molecular Genetic Testing in OECD Countries."
The committee is sponsored by the Organization for Economic Co-Operation and Development (OECD) and recently met in Paris, France. OECD's web site states that the group "provides a setting where governments can compare policy experiences, seek answers to common problems, identify good practice and work to co-ordinate domestic and international policies."
Dr. Matteson also serves as Executive Director of the American Board of Medical Genetics.
Gupta Writes Chapters for Manual of Cancer
Vinay Gupta, MD, Assistant Professor, Department of Surgery, has published two chapters in the latest edition of Holland-Frei Manual of Cancer Medicine, edited by Charles Brown and Brian Rini. The pocket handbook is set for release on June 1, 2005. Dr. Gupta's chapters included: Esophageal Cancer and Gastric Cancer.
Hudson Attends Academic Radiology Meeting
Kathleen
Hudson,MD, Assistant Professor, Department of Radiology and Program Director of the Radiology Residency Program, attended the Association of University Radiologists meeting held in Montreal, Canada in May. Mike Buehler, MD, and Matt Bowen, MD, Chief Radiology Residents for 2005-2006 academic year, also attended the chief resident section meetings.
Namey Publishes Book Chapter
Thomas Namey, MD, Professor, Department of Medicine, has authored a chapter in a 2005 textbook entitled, Aging Men's Health.
Dr. Namey's chapter, "The Effects of Aging, Hypogonadism, and Nutrition on Endurance and Strength," discusses the physiological aging in men.
Department of Family Medicine Receives "Reach Out and Read" Grant

Lorraine Wallace, PhD, and Steven Roskos, MD, faculty in the Department of Family Medicine, recently received a grant to implement the "Reach Out and Read Program" (ROR). The program will provide new books to children, ages six months to five years, during their "well child visits" to the department.
In addition to promoting pediatric literacy, the program helps physicians in giving advice to parents about reading aloud with their child, noting that reading aloud enhances language development. Currently there are more than 2,000 ROR programs throughout the United States. However, this is the first ROR program in East Tennessee. The Department of Family Medicine hopes to distribute several books per day. For more information, contact Dr. Wallace.
New Faculty Appointments:
- Tina Dudney, MD, Assistant Professor, Department of Medicine, Director of Pulmonary/Critical Care Fellowship Program
- Meixiang Yu, PhD, Associate Professor, Department of Medicine, Chief of the Division of PET Radiopharmaceutical Chemistry Research
- Wesley S. Mullins, DDS, Instructor, Department of General Dentistry
- John J. Snidow, MD, Assistant Professor, Department of Radiology
- Paul T. Wooten, MD, Associate Professor, Department of Radiology - Retired
Electronic Book Chapter Published
Robert R. Levey, PhD, MPH, Director of the Resident Assistance Program and Jo Ann Cornelius, MSN, Administrative Director, Office of Graduate Medical Education, have recently completed a chapter in a web-based textbook. The book is entitled, "Guide to Medical Education in the Teaching Hospital" and is published by the Association for Hospital Medical Education (AHME). Their chapter is entitled, "Nonacademic Assistance Programs." The online textbook does require a subscription.
Dr. Levey also serves as Associate Professor of Medicine and Psychiatry.

Pathology Faculty & Frances K. Patterson Resident Awards
The First Annual Frances K. Patterson Resident Award was presented to Dr. Jeffrey Johnston. The Patterson Award is given in memory of Dr. Frances K. Patterson. Dr. Patterson, who passed away in January 2005, was a devoted teacher and long-time faculty member. She served as Associate Professor in the Department of Pathology and Director of the Pathology Residency Program for more than ten years. The award is given to the resident who by their actions, has fostered excellence in education, research, practice or community services. The resident is selected by departmental faculty members.
The Pathology Faculty Award presented by pathology residents honored Alan Grindstaff, MD, Assistant Professor, and John Neff, MD, Professor for their outstanding teaching.
Medicine Residents Receive Rawson Award
The Rawson award, given in memory of long-time Department of Medicine faculty member, Freeman Rawson, MD, was presented to Dr. Wes Hayes, third year Internal Medicine Resident and Dr. Michael Henderson, second year Internal Medicine Resident. The award is given annually to two upper level residents who embody the "spirit of teaching and possess excellent clinical skills."

Dr. Rawson, who passed away in 2003, was a founding member of the Knoxville Cardiovascular Group and practiced medicine in Knoxville for 47 years. After his retirement from private practice, he devoted his time to teaching residents, medical students, and faculty in the Department of Medicine. Dr. Rawson was well known for his compassion and clinical skills.
Phipps Receives Master's Degree from CEM Program
Jonathan Phipps received his Master's Degree from the Comparative and Experimental Medicine (CEM) program while working with Dr. Michael Karlstadt, PhD, Professor of Surgery and Director of the Surgical Research. His thesis is entitled, "Effect of dietary treatment with stearidonic acid and eicosapentaenoic acid on membrane phospholipids fatty acid composition and glycogen-elicited peritoneal neutrophil viability in absence or presence of bacterial endotoxins." Phipps has also been accepted in the PhD program and will be under the mentorship of Jonathan Wall, PhD.

Medicine Department Recruitment DVD Wins Advertising Awards
The Department of Medicine and Marketing Communications Agency, Davis Newman Payne, coordinated by Susan Wyatt of the UT Medical Center's Marketing Department, worked together to produce a DVD to provide information to potential applicants to the program. The DVD features residents and faculty discussing outstanding qualities of the program, the institution and the Knoxville area.
The DVD has received the following advertising awards:
View the video. (Your computer must have RealPlayer to view. Download RealPlayer. )
Anesthesiology News:
Medical Genetics News:
- Darla Henderson, RD, MPH, Metabolic Nutritionist for the Department of Medical Genetics, has been elected Chair of the Professional Issues Committee of the Knoxville District Dietetic Association (KDDA).
- David W. Hollar, PhD, has been appointed to a two-year term on the editorial board of the Maternal and Child Health Journal beginning Fall 2005. Dr. Hollar will also serve on a grant review panel for this year's Field Initiated Review Program Competition being conducted by the National Institute on Disability and Rehabilitation Research (NIDRR), U.S. Department of Education.
- Carmen Lozzio, MD, Professor, has been appointed to the U.S. Department of Health and Human Services Agency for Healthcare Research Quality (AHRQ) Steering Committee on Health Information Technology.
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