The Scope E-Newsletter
From the Dean's Office
In the Spotlight
Researchers Earn Doctorate Degrees
Dustin Osborne, Assistant Professor, Radiology, has earned his PhD in Nuclear Engineering (Radiological Engineering) effective December 2011. His dissertation, "Characterization of a Small Animal SPECT Platform for use in Preclinical Translational Research," focused on the performance of SPECT to image I-125 and determine areas for improvement.
Dr. Osborne works in the Molecular Imaging and Translational Research Program (MITRP) area of Radiology as an imaging specialist and physicist providing technical expertise with regard to developing experiments, optimizing the conditions under which the experiments are performed, and analysis of data acquired from the imaging systems. Dr. Osborne also provides business development support to the MITRP, including driving collaborations and working to create an educational infrastructure within the group.
Jonathan Phipps also graduated with his PhD in December 2011 through the UT Comparative and Experimental Medicine Program, conducting research under the guidance of Jonathan Wall, PhD, Director of the Preclinical Diagnostic and Molecular Imaging Laboratory. His research, "Toward Personalized Medicine: The Potential Role of RNA Interference in Plasma Cell Dyscrasias," investigated the ability to apply a fairly novel method of gene regulation, RNA interference, to reduce protein burden in patients with amyloidosis and other plasma cell disorders. Dr. Phipps also developed and generated a virus-based delivery system which is used to deliver a modified version of interfering RNA to knock down the ability of cells to produce immunoglobulin components in a semi-permanent fashion. Dr. Phipps now works as a post-doctorate researcher in the Human Immunology and Cancer Program with Daniel Kestler, PhD, Assistant Professor, studying a protein called ODAM, which has been proposed as a biomarker in breast cancer.
Tatiana Perevozchikova, who was working as a Graduate Student in the Conformational Diseases and Therapeutics Research Program under the direction of Valerie Berthelier, PhD, received her doctorate in January. She studied "Structural Dynamics of Huntingtin Exon 1 Aggregation Studied By Small Angle Neutron Scattering" in collaboration with the Spallation Neutron Source at Oak Ridge National Laboratory. As a graduate student, Dr. Perevozchikova made several presentations at international meetings and won awards, including Best Research Presentation Prize from the National School on Neutron and X-ray Scattering. She is now a post-doctorate researcher for nSoft at the National Institute of Standards and Technology under the U.S. Department of Commerce in Maryland.
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University of Tennessee