The Scope E-Newsletter January 2010

As we reach the mid-point of our academic year, this issue illustrates how active our faculty and staff are at local, regional, national and international levels with activities ranging from patient care to cutting-edge research. We should be particularly proud of our UT Genetics Center for the collaborative efforts with Johns Hopkins University in discovering the gene for Huntington Disease-Like 2. As one of four testing sites worldwide for this disorder, the Center is recognized as a distinctive leader. Other articles show that our faculty continue to display their prowess in the research and professional service realms as well as providing excellent care for our patients. Special congratulations to them and to our residents and staff who received kudos for their accomplishments. Each issue of The Scope reminds me of how fortunate we are to have the Graduate School of Medicine and the University of Tennessee Medical Center in our community.

James J. Neutens, PhD, FASHA
Dean

Dean's Retreat Drs. Mark Mckinney, Amy Leblanc, George Kabalka, and Kathleen Hudson

The Third Annual Dean's Retreat, held in December, brought together UT Graduate School of Medicine Department Chairs, Program Directors and Service Office Directors as well as representatives from the colleges of Nursing and Pharmacy and University Health Systems, to discuss opportunities to progress the research enterprise from good to great.

"As an Academic Medical Center," said Dean Jim J. Neutens, PhD, "this is an essential step in defining who we are and what we do for the community as well as the region."

In fact, the importance of research is reflected in the core values of the strategic plan developed in 2009 by Graduate School of Medicine and UHS administrators to promote basic science and clinically relevant research and to cultivate physicians to be educational scholars, lifelong learners and informed consumers of clinical research. Tactics include creating an Office of Medical Education and Research, increasing the number of faculty who produce scholarly activity, and increasing the number of fellows and residents who produce scholarly activity.

The Graduate School of Medicine currently has several resources available to support research success including an institutional review board, research laboratories, collaborations with external enterprises, statisticians, hospital personnel including nursing and risk management, and grant fund management through the business office.

The retreat included presentations by Amy Paganelli, Assistant Dean of Finance and Administration, on financial aspects of research including current grants and partnerships, and by Mitchell Goldman, MD, Chair and Residency Program Director of Surgery, discussing his department's success of combining research and scholarly activity. This leads to positive effects on accreditation, faculty recruitment, and the ultimate goal of developing the "complete" doctor.

Dean Neutens noted the retreat was a starting point for discussions among departments to determine opportune areas for research; potential collaborators, both internal and external; whether current research activities are adequate for program re-accreditation; and what needs must be met to enhance research within the departments. As the Graduate School of Medicine moves research from good to great, it will increase its collaborations and strengthen its relationships within the University system and throughout the community.

Huntington Disease is a progressive, genetic neurodegenerative disorder that typically appears in middle age and affects muscle coordination and cognitive functions. In the 1990s, a family in North Carolina showed symptoms of the disabling disease, but testing for mutation in the gene which is responsible for Huntington disease did not detect a causative mutation. Through testing in the UT Genetics Center Molecular Diagnostic Laboratory, in association with researchers at Johns Hopkins University School of Medicine, it was discovered that the mutated gene was different than the one associated with Huntington Disease. The newly discovered disease was named Huntington Disease-Like 2 for its similarities to the more common disorder. Today, the UT Genetics Center is the only laboratory in the U.S. that offers the HDL2 test and is one of only four testing sites worldwide.

The UT Genetics Center is part of the UT Graduate School of Medicine and is instrumental in our clinical practice, research and academic missions. Learn more about the services available at the UT Genetics Center on its new web site.

Several years ago, clinical faculty in Surgery's Division of Vascular/Transplant Surgery discovered that women receiving hormone replacement therapy (HRT) who presented with vascular disease requiring intervention often had more adverse outcomes after their procedures than women who were not taking HRT. They found that women taking HRT experience failed vascular interventions because of the development of intimal hyperplasia, a thickening of the arterial wall, causing arterial stenosis, a decrease in vessel diameter and reduced blood flow.

Investigators in the Vascular Research Laboratory are now on a mission to identify the vascular cell mechanisms that are influenced by estrogen and progesterone. Led by Deidra Mountain, PhD, Assistant Professor of Surgery's Division of Vascular/Transplant Surgery and Research Scientist in the Vascular Research Laboratory, their goal is to develop possible therapeutic interventions to improve outcomes for these affected women.

Vascular disease is the leading cause of morbidity in the U.S., and cases are expected to rise by 75 percent over the next 35 years. Although estrogen was the second most frequently prescribed medication in the U.S. in 2000, surveys show 58 percent of women stopped taking HRT due to possible increased risks for breast cancer and heart disease; however, many women still use HRT for relief of menopausal symptoms.

Dr. Mountain believes the need for therapeutic intervention to HRT's adverse effects on vascular interventions is increasingly important, and the American Heart Association (AHA) agrees. Dr. Mountain's project is funded in part through a four-year Scientist Development Grant from the AHA. Comments for the grant approval included that the problem is of "significant clinical importance" given the prevalence of vascular disease and the seemingly contradictory reports of the risks and benefits associated with HRT use. Additionally, the reviewers commented on the "supportive environment" at the UT Graduate School of Medicine, including the availability of resources and the dedication of Surgery faculty, including Mitchell Goldman, MD, Chair, to advance the practice of medicine through basic, translational and clinical research.

"Things can be discovered and solved in a basic science laboratory that are often left unanswered in retrospective or prospective clinical studies alone," Dr. Mountain said. "But if it stays in the laboratory and never makes it back to the clinic, then what was the point? What is gratifying about the work we do here is the collaboration between basic, translational, and clinical science all working together."

While breast cancer research has led to advancements in treatment options and increased survival rates over the past 15 years, oral cancer research has made little progress. Oral cancers, represented by squamous cell carcinoma, are the tenth most common cancers in the United States, and even higher in East Tennessee due to smoking and other social habits such as the use of smokeless tobacco.

David Gerard, PhD, Professor of Oral and Maxillofacial Surgery and Director of Research; and Eric Carlson, DMD, MD, FACS, Professor and Chairman of the Department of Oral and Maxillofacial Surgery, want to improve the survivability associated with oral cancer by being able to predict a cancer's biologic behavior with subsequent targeted therapy. They have designed a study in an attempt to identify a "genetic signature" for oral cancers that behave in different ways. After two pilot studies, the investigators discovered that oral squamous cell carcinoma may behave in one of three ways: the cancer remains isolated to the oral cavity without regional lymph node or distant metastatic spread despite the potential for bone invasion; the cancer spreads quickly to regional lymph nodes in the neck; or the cancer spreads to the lymph nodes in the neck as well as distant organs.

Using evidence collected from more than 200 operated cases of oral cancer with long-term follow-up of patients, the investigators will examine the genetic profile of these cancers and look for mutations in patients who had a recurrence of their cancer. Their goal is to identify genetic profiles of cancers that will permit surgical procedures and adjuvant therapy based on a predicted biologic behavior of the cancer.

In addition to studying oral cancers, Drs. Gerard and Carlson are studying a novel biomaterial made from hydroxyapatite, a naturally-occurring mineral found in bone and other hard tissues, as a bone replacement material, in collaboration with Oak Ridge National Laboratory. The novel material is produced by bacteria in culture, and therefore the calcium/phosphorus ratio can be modified by varying culture conditions to imitate the ratio found in human bone. This material has the potential to act as a bridge in bone defects and then stimulate the bone-growth process.

The Oral and Maxillofacial Surgery researchers have designed a third study that has the potential to improve outcomes for their patients who receive bisphosphonate therapy. Bisphosphonate medications are commonly used to treat patients with osteoporosis and metastatic cancer, including multiple myeloma, breast and prostate cancer. These patients who undergo oral surgical procedures may develop bisphophonate-related osteonecrosis of the jaw (BRONJ), or death of jawbone. Drs. Gerard and Carlson are looking at ways to override the negative effects on bisphosphonate treatment on bone activity.

"The integration of effort of clinicians and basic science researchers presents an exciting opportunity to make clinically meaningful conclusions in translational research performed in an academic medical center," Dr. Carlson said. "My hope is that my work with Dr. Gerard will one day result in my ability to more effectively manage cancer patients in my surgical practice."

Nationally-recognized physician Larry Kilgore, MD, has brought his expertise in diagnosing and treating women with cancer of the reproductive organs to the University of Tennessee Graduate School of Medicine as Professor and Chief of Obstetric and Gynecology's Division of Gynecologic Oncology.

Originally from East Tennessee, Dr. Kilgore built his career at the University of Alabama, Birmingham, in the Obstetrics and Gynecology department where he focused on patient care, the delivery of excellent service, and advanced cancer therapies, including robotic surgery and clinical research. When robotic surgery was approved for use in gynecologic oncology, Dr. Kilgore took it upon himself to be among the first trained so that he could offer his patients minimally invasive surgery that results in shorter hospital stays, quicker recoveries, less pain and smaller incisions.

At UAB Dr. Kilgore served as a Professor and held the J. Max Austin Endowed Chair in the Division of Gynecologic Oncology, he was a senior scientist for the UAB Comprehensive Cancer Center, fellowship director for gynecologic oncology, and residency program director in the Department of Obstetrics and Gynecology. Additionally, Dr. Kilgore has published more than 100 articles and serves as a board examiner for the American Board of Obstetrics and Gynecology and Specialty Boards in Gynecologic Oncology.

John Bell, MD, Professor and Chief, Surgery's Division of Surgical Oncology, said, "We are truly blessed to have a physician of Dr. Kilgore's caliber join our faculty. He brings the 'entire package' with his outstanding clinical care, proven academic skills and extraordinary teaching capabilities. We are thankful for his desire to be a part of our team."

Dr. Kilgore said the mission of the Graduate School of Medicine aligns with his personal values to focus on patient care, research and education.

"This is a call home for me. I love caring for patients, advancing robotic surgery, and training resident physicians and medical students. There are fascinating opportunities at the Graduate School of Medicine."

Esteemed by the community and welcomed home, Dr. Kilgore was recently featured in the Fall 2009 issue of Frontiers magazine and in the Physician Spotlight in East Tennessee Medical News.

The UT Graduate School of Medicine Medical Simulation Center held an open house sponsored by Simbionix to assess virtual reality simulation models. Faculty, residents, fellows, medical students and staff were invited to survey upper and lower GI (gastrointestinal) tracts; practice complete laparoscopic cholecystectomy; and practice bronchoscopy while receiving feedback and performance metrics from the computer-based simulators. The technologies included true-to-life case scenarios, including patients with varying anatomies, diverse pathologies, and reactive vital signs and complications.

Leonard Hines, MD, Co-Director, said, "Virtual reality simulation provides a significant opportunity for residents and staff alike to learn or review surgical techniques and improve performance in a risk-free environment outside the operating room. The potential availability of this technology at the Medical Simulation Center enables us to advance toward the level of sophistication we hope to reach in our curricula and training programs at the UT Graduate School of Medicine and the University of Tennessee Medical Center."

The open house provided an opportunity for Medical Simulation Center staff to become familiar with the virtual reality models available and determine which would best fit the needs of the Graduate School of Medicine.

The Medical Simulation Center opened its doors in 2008 and provides training opportunities on life-size human mannequins, laparoscopic simulators and other skills-building models. Under the direction of Dr. Hines; Co-Director Paul Huffstutter, MD; Melinda Klar, RN, Administrator; and Judy Roark, CST, Coordinator and Skills Coach, the Center is utilized by faculty, staff, residents, fellows and medical students for instruction, skills practice and simulation.

The Department of Medicine held its annual faculty award reception December 15, 2009.

Juli Williams, MD, and Timothy Panella, MD

Since the early 1980s, the Department of Medicine has had a yearly tradition of recognizing one teacher who deserves the accolade "excellent." The medicine residents vote for this deserving faculty member. The 2009 London Award was presented to Juli Williams, MD, Assistant Professor. Dr. Williams has been a faculty member since 2006. She was appointed to the position of Director of the Internal Medicine Residency Clinic this year. Dr. Williams has proven to be a very enthusiastic, dedicated and knowledgeable teacher.

The London Award is named in memory of the late Frank London, MD. Dr. London was the founding member of the Knoxville Cardiovascular Group and Professor in the Department of Medicine, where he served as Chief of Cardiovascular Medicine. Dr. London is remembered by his students as a faculty member who was accessible, dedicated and thoughtfully knowledgeable with regard to treating the disease and patient.

Daphne Norwood, MD, and Timothy Panella, MD

The Richard A. Obenour, Jr. Award is presented annually to a deserving faculty member for steadfast commitment to education and teaching. The 2009 recipient of this award was Daphne M. Norwood, MD, Assistant Professor of Medicine. Dr. Norwood has been an active faculty member in the Department of Medicine since 1996 and has served as Program Director for the Transitional Year Residency Program, developed a course on evidence-based medicine, and serves as an inpatient attending.

The Richard A. Obenour, Jr. Award was established after the untimely death of the son of Dr. and Mrs. Richard A. Obenour. The Obenour family, friends, and coworkers generously donated to an endowment fund in their son's memory. Since young Dick spent most of his life pursuing an education, Dr. Obenour thought it fitting to create an award dedicated to a faculty member who displayed a commitment to education through teaching residents and medical students.

A long standing faculty member, John H. Acker, MD, Clinical Assistant Professor of Medicine, was recognized with a 25 Years of Service Award. Dr. Acker has been an active faculty member in the department since 1984.

Radiology residents received high marks on the American Board of Radiology (ABR) Diagnostic Radiology exam. Passing the exam administered in September 2009 were fourth-year residents Cassy DiRuzzo, MD; Chris Guglielmo, MD; Jason Hill, MD; Monty Smith, MD; Rob Thurman, MD; and Nick Waddell, MD.

The following third-year residents passed the ABR General Radiologic Physics exam in September 2009: Cheryl DeWitt, MD; Jacob Pirkle, MD; and Delaney Santoro, MD.

Amanda Noyes, MS, CGC, passed the American Board of Genetic Counseling certification examination and is now a Certified Genetic Counselor (CGC). Noyes has worked for the UT Graduate School of Medicine Genetics Center since June 2007, seeing pediatric and adult patients. When a child is diagnosed with a genetic condition, Noyes meets with the family to discuss the condition, the inheritance risk and recurrence risk, and provide support to the family. She also counsels adults regarding family histories of genetic conditions, cancer gene susceptibility, Huntington Disease presymptomatic testing, multiple miscarriages, hemochromatosis and thrombophilia.

Radiology residents Chris Guglielmo, MD, and Jason Hill, MD, attended the Radiology Society of North America (RSNA) 2009 annual meeting held in Chicago, Illinois, November 29-December 4, 2009.

Dr. Guglielmo attended sessions for his role in the American Alliance of Academic Chief Residents in Radiology (A3CR2). The mission of the organization is to encourage residents and other trainees in academic pursuits, to involve the leadership of residency programs with the leaders of academic radiology, to encourage scientific inquiry among residents, and to provide a voice for academic radiology residents in the affairs of organized radiology.

Dr. Hill's role at the meeting was to help organize a resident chapter of the American College of Radiology (ACR) in Tennessee. The mission of the ACR is to serve patients and society by maximizing the value of radiology, radiation oncology, interventional radiology, nuclear medicine and medical physics by:

Kathleen Hudson, MD, Associate Professor and Residency Program Director, Radiology, has been selected as an examiner for the American Board of Radiology oral exam to be administered in Louisville, Kentucky, in May. Dr. Hudson previously served as an examiner in 2008.

Dr. Hudson will also serve as an author for the American College of Radiology In-Training Examination for Diagnostic Radiology Programs to be held in February. This will be her seventh year providing input on this exam.

Wahid T. Hanna, MD, Professor of Medicine, Chief, Hematology/Oncology Division, was the Honorary Chair at The Leukemia and Lymphoma Society's 2009 Light the Night Walk. Dr. Hanna has been involved in hematology/oncology research and the diagnosis and treatment of these diseases for 39 years and participated as the Light the Night Honorary Chair for two years. Light the Night is an annual event to bring hope to people battling blood cancers; raise funds for research; and provide financial assistance, educational materials and support programs to patients and their families.

Deborah Brown, Assistant Director, Business Administration, recently received certification for part two of the "Leading at UT" training series offered by Employee and Organizational Development at the University of Tennessee. "Part 2: UT Leaders Lighting the Way" certification consists of 70 hours of courses focused on advanced management concepts, particularly courses dealing with rules and regulations at UT. Brown previously completed the Communication Training and Part 1 of the series, which cover communication skills and the basic concepts of employee supervision, respectively.

Brown joined the UT Graduate School of Medicine in 2007 and has worked for the University since 2005. She has more than 30 years of accounting experience in both private and public organizations.

The University of Tennessee encourages faculty and staff to take advantage of professional development programs. These programs are designed to empower and enlighten employees who work at all levels in the university.

Anna Lisa Jones, MD, Clinical Instructor, Obstetrics and Gynecology

Walter Schoutko, MD, Assistant Professor, Obstetrics and Gynecology

Holli Freestone, Clinical Assistant III, Family Medicine

Through the Resident Business Course Lite series, resident physicians and dentists have the unique opportunity to gain essential business skills to prepare them for careers in a private practice, hospital or academic medical center setting.

New this series is the real estate course which will include timely information on all home-buyer tax credits with a focus on the first-time homebuyer, a comparison of owning versus renting, and the overall purchasing process.

Sessions will be held from noon-1p.m. in Wood Auditorium and include the following:

February 18, 2010: "Buying the Right Home for Your Budget and Needs with Focus on First Time Home Buyers" presented by Tricia Andrews and Megan Stansbury, Keller Williams Realty: The Laing Team

March 25, 2010: "Realistic Insurance Planning for Physicians" presented by Heath Hildreth, The Hildreth Agency

April 15, 2010: "The Importance of Your Starting Employment Contract: Pitfalls to Avoid" presented by London and Amburn, P.C., Attorneys at Law

April 29, 2010: "Personal Financial Management: A Roadmap for Medical Professionals" presented by Laura Lyons and Chad Schollaert, The Trust Company

May 20, 2010: "Your Money and Taxation: Business Advice from a Certified Public Accountant" presented by Amy Holley, Lattimore Black Morgan and Cain, PC

The 2010 course kicked off January 21 with keynote speaker Steve Ross, DPh, University Health Systems, discussing the professional and personal considerations of life after residency.

Residents have previously evaluated the course as practical, necessary and engaging, with speakers scoring high on knowledge and approachability. View presentations from the 2008-2009 series on the GSM Pulse.

Resident Business Course Lite is sponsored by UT Graduate School of Medicine Graduate Medical and Dental Education.

The second annual UT Graduate School of Medicine and Academy of Scholars Committee Resident Research Day will be Wednesday, May 26, in the College of Pharmacy third-floor auditorium. Residents are invited to participate by submitting a structured abstract for unpublished research by Monday, April 26.

Resident Research Day gives residents an opportunity to share their research via poster in PowerPoint format and a three-minute oral presentation. Presentations will be judged and awards will be given for first, second and third place and for best case presentation.

Download the 2010 Annual Resident Research Day abstract template (.doc). An example is also available.

For more information and to submit abstracts, contact Brenda Chaves, Administrative Specialist, Dean's Office.

Mark your calendars for these early 2010 Continuing Medical and Dental Education events, sponsored by the UT Graduate School of Medicine.

January 28: Surgery Grand Rounds: Transcontinental Surgery, Morrison's Conference Center, 7-8 a.m.

February 4: Surgery Grand Rounds: Lymphedema—Surgical and Conservative, Morrison's Conference Center, 7-8 a.m.

February 9: Internal Medicine Grand Rounds: Acute Pancreatitis, Morrison's Conference Center, 8-9 a.m.

February 11: Surgery Grand Rounds: Inflammatory Bowel Disease, Morrison's Conference Center, 7-8 a.m.

February 18: John W. Whittington, MD Visiting Lectureship: Melanoma as an Example of Evidence-based Medicine, Charles Balch, MD, Professor of Surgery, Oncology and Dermatology, Johns Hopkins University School of Medicine, Morrison's Conference Center, 7-8 a.m.

February 25: Surgery Grand Rounds: Mission Surgery, Morrison's Conference Center, 7-8 a.m.

March 4: Surgery Grand Rounds: TBA, Morrison's Conference Center, 7-8 a.m.

March 9: Internal Medicine Grand Rounds: Geriatric Medicine, Morrison's Conference Center, 8-9 a.m.

March 11: John W. Whittington, MD Visiting Lectureship: TBA, Morrison's Conference Center, 7-8 a.m.

March 13: Sixth Annual Diabetes Regional Conference: Evidence-Based Interventions to Stem the Burden of Diabetes Complications, UT Conference Center

March 18: Surgery Grand Rounds: Paraesophageal Hernia, Morrison's Conference Center, 7-8 a.m.

March 25: Surgery Grand Rounds: Physical Medicine and Rehabilitation, Morrison's Conference Center, 7-8 a.m.

March 26: Faculty Development Workshop, UT Conference Center

Visit CMDE Upcoming Courses or contact Communications and Outreach for more information about these activities.

All UTGSM faculty are invited to attend the second annual Faculty Development Workshop, Friday, March 26, UT Conference Center, 8 a.m.–12:00 p.m., presented by the UTGSM and Academy of Scholars Committee. Registration will open soon.

Two keynote presenters, Dr. Pamela Rowland from Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, and Dr. Sheila Chauvin from Louisiana State University Health Science Center, New Orleans, Louisiana, will address "Professionalism" and "Scholarly Research in Medical Education."

After the two plenary presentations, participants will attend workshops to apply the material covered in the plenary sessions. A continental breakfast and box lunch will be provided.

This workshop will offer CMEs through AMA and AAPA. Watch for more details and registration information.

The April 16 meeting of the East Tennessee Dermatology Society will be CME-certified, so make plans to attend this meeting, to be held at 4-6 p.m. at Knoxville Dermatology Group, Suite 209, UT Medical Center. This activity offers up to 2 CME credits through AMA and AAPA and up to .2 CEUs. Presenters will discuss the unusual presentations of dermatologic disorders and diseases that are refractory to typical therapy. Items to be covered are pathology, dermatologic disorders and their mimics, and treatment strategies.

To register and for more information, contact Charlsie Huffstetler, Knoxville Dermatology Group, 342-5808.

Register today for the Sixth Annual Diabetes Regional Conference: Evidence-Based Interventions to Stem the Burden of Diabetes Complications, Saturday, March 13, 7:45 a.m.-4:30 p.m., UT Conference Center. This course offers up to 6 AMA, AAFP, AAPA and ACPE credits or .6 CEUs.

While the cost, morbidity and mortality from diabetes, itself, is high, its numerous complications and associated risk factors account for the overwhelming burden of this disease. Healthcare professionals play a pivotal role in stemming these health consequences by learning and applying the most recent evidence-based treatment strategies and interventions.

In response to participant evaluations of past diabetes conferences, the 2010 conference will address patient noncompliance in addition to latest medical research into ophthalmological, cardiovascular, vascular and renal complications of diabetes. Specialists in these and other fields, including nutrition and psychology, will offer knowledge to help physicians help their diabetic patients.

Check out all details and register at www.tennessee.edu/cme/Diabetes2010.

The weekly Surgery Grand Rounds, held Thursdays, 7-8 a.m., in Morrison's Conference Center, offer up to 1 CME credit per session, and this year, the Grand Rounds will include the John W. Whittington, MD Visiting Lectureship series, bringing specialists from across the country to the UTGSM. Whittington lectures will be held during regularly scheduled Grand Rounds times and will be offered several times each year.

Other CME-certified grand rounds include the Internal Medicine Grand Rounds, held the second Tuesday of each month, 8-9 a.m., Morrison's Conference Center. Each session offers up to 1 CME credit.

Neurology/Neurosurgery Quarterly Case Conferences, presented by the Brain and Spine Institute, also are CME-certified and are held the third Monday of the first month of each quarter. They offer up to 1 CME credit per session and are held 7-8 a.m., Morrison's Conference Center.

Visit Continuing Medical and Dental Education Courses to see a listing of all grand rounds and quarterly case conferences. Also watch the news monitors throughout the medical center and Graduate School of Medicine for reminders.

Southern Medical Association's Annual Scientific Assembly, Dallas, Texas, December 3–5, 2009

Poster Presentation
Ronald Lands, MD
"Deficiency in Anemic Inpatients at University of Tennessee Medical Center, Knoxville."

National Society of Genetic Counselors Annual Education Conference, Atlanta, Georgia, November 12-15, 2009

Poster Presentation
Abbey Putnam, MS
"Dominant vs. Non-dominant Hand Strength in CMT1A."

Brown KC, Fitzhugh EC, Neutens JJ, Klein DA
Screening mammography utilization in Tennessee women: the association with residence.
J Rural Health. 2009 Spring;25(2):167-73.
PMID: 19785582

Carroll RC, Worthington RE, Craft RM, Snider CC, Dakin PA, Wortham DC, Scott J, Jarrett A
Post interventional cardiology urinary thromboxane correlates with PlateletMapping(R) detected aspirin resistance.
Thromb Res. 2009 Dec 3.
PMID: 19962724

Wallace LS, DeVoe JE, Rogers ES, Protheroe J, Rowlands G, Fryer GE Jr.
Digging deeper: quality of patient-provider communication across Hispanic subgroups.
BMC Health Serv Res. 2009 Dec 21;9:240.
PMID: 20025725

Bukovsky A
Sex steroid-mediated reprogramming of vascular smooth muscle cells to stem cells and neurons: possible utilization of sex steroid combinations for regenerative treatment without utilization of in vitro developed stem cells.
Cell Cycle. 2009 Dec 15;8(24):4079-84. Epub 2009 Dec 21.
PMID: 19946214

Adekar SP, Klyubin I, Macy S, Rowan MJ, Solomon A, Dessain SK, O'Nuallain B
Inherent anti-amyloidogenic activity of human immunoglobulin gamma heavy chains.
J Biol Chem. 2010 Jan 8;285(2):1066-74. Epub 2009 Nov 4.
PMID: 19889627

Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW
Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.
Neuron. 2009 Dec 24;64(6):828-40.
PMID: 20064390

Kendrick, JM
(2010). Diabetes in Pregnancy 4th Ed.
(Series, Module) New York: March of Dimes Birth Defects
Foundation.