The Department of Medicine
Joseph W. Jackson, PhD
Assistant Professor
Division of Research
Research
https://orcid.org/0000-0003-1572-6907
Research Focus
Amyloidosis and Cancer Theranostics
Education
Doctorate
The Univeristy Of Tennessee, Knoxville TN, 2019
Fellowship
Pittsburgh School of Medicine, Pittsburgh, PA, 2021
Honors and Awards
National Institutes of Health, Addressing Collagen Mediated Protection of Systemic Amyloid Fibrils 1R01AI184456-01 September 2024-August 2028
National Institutes of Health & University of Pittsburgh, Circumventing Barriers to Effective Oncolytic Virotherapy of Malignant Gliomas P01 CA163205 Chiocca (PI), Role: Coinvestigator Project 1, September 2023-August 2028
International Workshop on Translational in Systemic Amyloidosis, Early Career Travel Award , 2023
International Symposium on Amyloidosis and International Society of Amyloidosis, Presidential Award, 2022
University of Tennessee, Chancellor’s Award for Extraordinary Professional Promise, 2019
Current Publications
Hancock TJ, Vlasyuk M, Foster JS, Macy S, Wooliver DC, Balachandran M, Williams AD, Martin EB, Kennel SJ, Heidel ER, Wall JS, Jackson JW..
Neutrophils enhance the clearance of systemic amyloid deposits in a murine amyloidoma model. Front Immunol. 2024 Nov 12;15:1487250. doi: 10.3389/fimmu.2024.1487250. eCollection 2024.
Wall JS, Kennel SJ, Stuckey A,Whittle B, Jackson JW, Williams AD, Hancock T, R. Heidel R, Mehmood M, Kassira A, Lands RH, Watson H, Hung R, Martin EB.
Preliminary observations using 99m-Tc-peptide P5+14 for the detection of AL amyloidosis using SPECT/CT and planar gamma scintigraphic imaging. Blood. 2024,Volume 144, Supplement 1,Page 1910,ISSN 0006-4971,https://doi.org/10.1182/blood-2024-207978.
Wall JS, Kennel SJ, Stuckey A, Richey T, Williams AD, Balachandran M, Hancock T, Jackson JW, Wooliver DC, Macy S, Heidel ER, Lands RH, Martin EB.
Characterization of AT02 bioactivity and an assessment of its potential use as an amyloid-clearing therapeutic for AL amyloidosis. Blood. 2024,Volume 144, Supplement 1,,Page 4641,ISSN 0006-4971, https://doi.org/10.1182/blood-2024-208282.
Wall JS, Martin EB, Stuckey A, Whittle B, Jackson JW, Williams A,Hancock T, Heidel ER, Mehmood M, Kassira A, Watson H, Hung R, Kennel S.
Early evaluation of 99mTc-labeled peptide P5+14 for the detection of cardiac amyloidosis using SPECT/CT and planar gamma scintigraphic imaging. Journal of Nuclear Cardiology. 2024,Volume 38, Supplement,102002,ISSN 1071-3581,https://doi.org/10.1016/j.nuclcard.2024.102002.
Wall J, Martin E, Stuckey A, Whittle B, Jackson J, Williams A, Hancock T, Heidel ER, Mehmood M, Kassira A, Lands R, Watson H, Hung R, Kennel S.
Preliminary evaluation of 99mTc-labeled peptide P5+14 for the detection of cardiopulmonary amyloidosis using SPECT/CT and planar gamma scintigraphic imaging. Journal of Nuclear Medicine. Jun 2024, 65 (supplement 2) 241277
Wall J, Martin E , Heidel R, Stuckey A, Whittle B, Jackson J, Williams A, Mehmood M, Kanderian A, Rebecca K, Hung R, Lands R, Kennel S.
Detection of amyloid cardiomyopathy in patients with systemic ATTR and AL amyloidosis using SPECT/CT and planar imaging of a technetium-99m-labeled peptide - technetium-99m (99mTc) evuzamitide. Journal of the American College of Cardiology . 2024 Apr, 83 (13_Supplement) 1369.https://doi.org/10.1016/S0735-1097(24)03359-X
Kennel SJ, Jackson JW, Stuckey A, Richey T, Foster JS, Wall JS.
Preclinical evaluation of Tc-99m p5+14 peptide for spect detection of cardiac amyloidosis. PLoS One. 2024 Apr 5;19(4):e0301756. doi: 10.1371/journal.pone.0301756. eCollection 2024.
Foster JS, Balachandran M, Hancock TJ, Martin EB, Macy S, Wooliver C, Richey T, Stuckey A, Williams AD, Jackson JW, Kennel SJ, Wall JS.
Development and characterization of a prototypic pan-amyloid clearing agent - a novel murine peptide-immunoglobulin fusion. Front Immunol. 2023 Oct 2;14:1275372. doi: 10.3389/fimmu.2023.1275372. eCollection 2023.
Jackson JW, Foster JS, Martin EB, Macy S, Wooliver C, Balachandran M, Richey T, Heidel RE, Williams AD, Kennel SJ, Wall JS.
Collagen inhibits phagocytosis of amyloid in vitro and in vivo and may act as a 'don't eat me' signal. Amyloid. 2023 Sep;30(3):249-260. doi: 10.1080/13506129.2022.2155133. Epub 2022 Dec 21.